Back to top

The current mutation

ID: V3352
DNA: 20143T>C
Protein: F6715L
Position: 20407








COV2Var annotation categories







Summary information of mutation (20143T>C)

Basic Information about Mutation.

  Gene Information   Gene ID   GU280_gp01_pp1ab
  Gene Name   ORF1ab_pp1ab
  Gene Type   protein_coding
  Genome position   20407
  Reference genome   GenBank ID: NC_045512.2
  Mutation type   missense_variant
  DNA Level   DNA Mutation: 20143T>C
  Ref Seq: T
  Mut Seq: C
  Protein Level   Protein 1-letter Mutation: F6715L
  Protein 3-letter Mutation: Phe6715Leu

Overview of the genomic positions of Mutation.
Note: The annotated 12 genes were retrieved from GeneBank (Accession: NC_045512.2). "MP" represents genomic position of mutation.





Analyzing the distribution of mutation (20143T>C) across geographic regions, temporal trends, and lineages

The count of genome sequences harboring this mutation and its distribution across global regions offer insights into regional variations.
Note: The distribution of mutation across 218 geographical regions. Color representation of genome sequence counts. The data is obtained from GISAID's metadata, specifically capturing the regional distribution of genomic sequences.



The dynamic count of genome sequences containing this mutation over time.
Note: Clicking the "Count" or "Cumulative Count" button toggles the view. Count represents the number of genome sequences per month. Cumulative count represents the accumulated total count up to the respective month. The data is obtained from GISAID's metadata, specifically capturing the collection date of genomic sequences.



For every time point represented in the graph above, identifying the top 3 lineages with the highest count of genome sequences carrying this mutation aids in pinpointing noteworthy lineages for further analysis.
Note: Users can filter the lineages by entering a "Year-Month" term in the search box. For example, entering 2020-01 will display lineages that appeared in January 2020. The data is obtained from GISAID's metadata, specifically capturing the collection date of genomic sequences.

Collection date Lineage Total lineage monthly counts Lineage-specific monthly counts Lineage-specific monthly frequency
2020-10 B.1.1.37 28 23 8.21e-1
2020-10 B.1.1.303 28 4 1.43e-1
2020-10 B.1 28 1 3.57e-2
2020-11 B.1.1 7 2 2.86e-1
2020-11 B.1.1.303 7 2 2.86e-1
2020-11 B.1.177 7 1 1.43e-1
2020-12 B.1.2 9 5 5.56e-1
2020-12 B.1.351 9 2 2.22e-1
2020-12 B.1.160 9 1 1.11e-1
2020-04 B.1 1 1 1.00e+0
2020-05 B 3 2 6.67e-1
2020-05 B.1 3 1 3.33e-1
2020-07 BA.1 4 2 5.00e-1
2020-07 A 4 1 2.50e-1
2020-07 B.1.546 4 1 2.50e-1
2020-08 B.1.1.269 4 4 1.00e+0
2020-09 B.1.1.37 30 21 7.00e-1
2020-09 B.1.1.269 30 9 3.00e-1
2021-01 B.1.2 11 3 2.73e-1
2021-01 B.1.1 11 2 1.82e-1
2021-01 B.1.1.7 11 2 1.82e-1
2021-10 AY.5 167 143 8.56e-1
2021-10 AY.103 167 9 5.39e-2
2021-10 C.37 167 5 2.99e-2
2021-11 AY.5 630 555 8.81e-1
2021-11 AY.103 630 58 9.21e-2
2021-11 AY.43 630 8 1.27e-2
2021-12 AY.5 274 209 7.63e-1
2021-12 AY.29 274 22 8.03e-2
2021-12 AY.103 274 17 6.20e-2
2021-02 B.1.177 24 8 3.33e-1
2021-02 B.1.2 24 6 2.50e-1
2021-02 B.1.1.7 24 3 1.25e-1
2021-03 B.1.1.7 29 14 4.83e-1
2021-03 B.1.1.37 29 3 1.03e-1
2021-03 B.1.1.519 29 3 1.03e-1
2021-04 B.1.1.7 54 32 5.93e-1
2021-04 Q.4 54 7 1.30e-1
2021-04 P.1 54 4 7.41e-2
2021-05 B.1.632 26 10 3.85e-1
2021-05 B.1.1.7 26 9 3.46e-1
2021-05 B.1.351 26 3 1.15e-1
2021-06 B.1.632 59 28 4.75e-1
2021-06 B.1.1.7 59 22 3.73e-1
2021-06 C.37 59 2 3.39e-2
2021-07 B.1.632 87 66 7.59e-1
2021-07 AY.3 87 6 6.90e-2
2021-07 XB 87 4 4.60e-2
2021-08 B.1.632 56 40 7.14e-1
2021-08 AY.3 56 5 8.93e-2
2021-08 AY.103 56 3 5.36e-2
2021-09 AY.103 53 27 5.09e-1
2021-09 AY.5 53 8 1.51e-1
2021-09 AY.27 53 5 9.43e-2
2022-01 AY.29 117 37 3.16e-1
2022-01 BA.2 117 24 2.05e-1
2022-01 AY.5 117 21 1.79e-1
2022-10 BF.14 45 38 8.44e-1
2022-10 BA.4.6.5 45 2 4.44e-2
2022-10 AY.103 45 1 2.22e-2
2022-11 BF.14 29 20 6.90e-1
2022-11 BA.2.3 29 3 1.03e-1
2022-11 BA.2.3.20 29 2 6.90e-2
2022-12 BF.14 26 20 7.69e-1
2022-12 BQ.1.1.11 26 2 7.69e-2
2022-12 BF.7 26 1 3.85e-2
2022-02 BA.2 122 94 7.70e-1
2022-02 BA.1.1 122 8 6.56e-2
2022-02 BA.2.10 122 7 5.74e-2
2022-03 BA.2 313 270 8.63e-1
2022-03 BA.2.3 313 23 7.35e-2
2022-03 BA.1.1 313 11 3.51e-2
2022-04 BA.2 173 135 7.80e-1
2022-04 BA.2.3 173 24 1.39e-1
2022-04 BA.2.3.18 173 5 2.89e-2
2022-05 BA.2 68 37 5.44e-1
2022-05 BA.2.38 68 25 3.68e-1
2022-05 BA.2.3 68 2 2.94e-2
2022-06 BA.2.38 104 90 8.65e-1
2022-06 BA.2 104 9 8.65e-2
2022-06 BA.2.3.18 104 3 2.88e-2
2022-07 BA.2.38 35 26 7.43e-1
2022-07 BA.5.2.9 35 2 5.71e-2
2022-07 BA.2 35 1 2.86e-2
2022-08 BF.14 13 8 6.15e-1
2022-08 BA.5.2.22 13 2 1.54e-1
2022-08 BA.2.3.2 13 1 7.69e-2
2022-09 BF.14 38 32 8.42e-1
2022-09 BA.5.2.22 38 2 5.26e-2
2022-09 BE.1 38 2 5.26e-2
2023-01 BN.1.2 20 6 3.00e-1
2023-01 BF.14 20 5 2.50e-1
2023-01 BA.2.3.20 20 2 1.00e-1
2023-02 BF.14 5 2 4.00e-1
2023-02 BN.1.2 5 2 4.00e-1
2023-02 XBB.1.9 5 1 2.00e-1

The count of genome sequences and the frequency of this mutation in each lineage.
Note: Displaying mutation frequencies (>0.01) among 2,735 lineages. Mutation Count represents the count of sequences carrying this mutation. Users can filter the lineages by entering a search term in the search box. For example, entering "A.1" will display A.1 lineages. The data is obtained from GISAID's metadata, specifically capturing the lineage of genomic sequences. Mutation count: Count of sequences carrying this mutation.

Mutation ID Lineage Mutation frequency Mutation count Earliest lineage emergence Latest lineage emergence
V3352 AY.5 1.52e-2 938 2020-9-8 2022-7-26
V3352 B.1.1.269 2.33e-2 13 2020-5-19 2021-7-10
V3352 B.1.1.37 1.04e-2 51 2020-3-23 2021-9-29
V3352 B.1.632 9.93e-1 150 2021-4-19 2021-9-22
V3352 BA.2.3.18 1.29e-2 9 2022-1-19 2022-8-19
V3352 BA.2.38 2.04e-2 144 2022-1-7 2022-10-24
V3352 BF.14 2.05e-2 125 2022-1-16 2023-2-16






Examining mutation (20143T>C) found in abundant sequences of non-human animal hosts

Exploring mutation presence across 35 non-human animal hosts for cross-species transmission.
Note: We retained the mutation that appear in at least three non-human animal hosts' sequences. The data is obtained from GISAID's metadata, specifically capturing the host of genomic sequences.

Animal host Lineage Source region Collection date Accession ID
Rhinolophus pusillus A Laos 2020-7-7 EPI_ISL_4302645
Rhinolophus marshalli BA.1 Laos 2020-7-10 EPI_ISL_4302647
Rhinolophus malayanus BA.1 Laos 2020-7-5 EPI_ISL_4302644
Rhinolophus pusillus B China 2020-5-25 EPI_ISL_1699446
Rhinolophus pusillus B China 2020-5-25 EPI_ISL_1663616




Association between mutation (20143T>C) and patients of different ages, genders, and statuses

Note: The logistic regression model was employed to examine changes in patient data before and after the mutation. The logistic regression model was conducted using the glm function in R. The data is obtained from GISAID's metadata, specifically capturing the patient status, gender, and age of genomic sequences.

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient statuses (ambulatory, deceased, homebound, hospitalized, mild, and recovered) based on GISAID classifications. In the analysis exploring the association between mutation and patient status, the model included mutation, patient status, patient age, gender, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient status Ambulatory -9.25e-1 4.80e-1 -1.93e+0 5.38e-2 Decrease
Deceased 2.04e+0 7.97e-1 2.56e+0 1.05e-2 Increase
Homebound -1.49e+1 1.56e+3 -9.52e-3 9.92e-1 Decrease
Hospitalized -6.83e-1 3.63e-1 -1.88e+0 5.99e-2 Decrease
Mild -4.67e-1 9.74e-1 -4.79e-1 6.32e-1 Decrease
Recovered -2.80e-1 3.99e-1 -7.02e-1 4.83e-1 Decrease

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient age (0-17, 18-39, 40-64, 65-84, and 85+). In the analysis exploring the association between mutation and patient age, the model included mutation, patient age, gender, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient age, years 0-17 9.42e-2 1.05e-1 8.98e-1 3.69e-1 Increase
18-39 -3.96e-1 6.37e-2 -6.20e+0 5.47e-10 Decrease
40-64 4.42e-2 6.30e-2 7.01e-1 4.83e-1 Increase
65-84 4.61e-1 7.79e-2 5.92e+0 3.21e-9 Increase
>=85 5.05e-1 1.41e-1 3.59e+0 3.34e-4 Increase

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient gender (male and female). In the analysis exploring the association between mutation and patient gender, the model included mutation, patient gender, patient age, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient gender Male -8.94e-2 6.01e-2 -1.49e+0 1.37e-1 Decrease





Investigating natural selection at mutation (20143T>C) site for genetic adaptation and diversity

Note: Investigating the occurrence of positive selection or negative selection at this mutation site reveals implications for genetic adaptation and diversity.

The MEME method within the HyPhy software was employed to analyze positive selection. MEME: episodic selection.
Note: List of sites found to be under episodic selection by MEME (p < 0.05). "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site P-value Lineage Method

The FEL method within the HyPhy software was employed to analyze both positive and negative selection. FEL: pervasive selection on samll datasets.
Note: List of sites found to be under pervasive selection by FEL (p < 0.05). A beta value greater than alpha signifies positive selection, while a beta value smaller than alpha signifies negative selection. "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site Alpha Beta P-value Lineage Method
endornase 19621 20658 346 263 12.28 0.00 4.00e-2 BA.2.65 FEL
endornase 19621 20658 346 263 15.76 0.00 5.00e-2 BM.1.1.3 FEL
endornase 19621 20658 346 263 21.71 0.00 4.00e-2 AY.108 FEL
endornase 19621 20658 346 263 10.70 0.00 5.00e-2 AY.57 FEL
endornase 19621 20658 346 263 12.31 0.80 1.00e-2 BA.5.1 FEL

The FUBAR method within the HyPhy software was employed to analyze both positive and negative selection. FUBAR: pervasive selection on large datasets.
Note: List of sites found to be under pervasive selection by FUBAR (prob > 0.95). A prob[alpha < beta] value exceeding 0.95 indicates positive selection, while a prob[alpha > beta] value exceeding 0.95 indicates negative selection. "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site Prob[alpha>beta] Prob[alpha<beta] Lineage Method
endornase 19621 20658 346 263 2.00e-2 9.60e-1 BF.14 FUBAR
endornase 19621 20658 346 263 9.90e-1 0.00e+0 BA.5.1 FUBAR




Alterations in protein physicochemical properties induced by mutation (20143T>C)

Understanding the alterations in protein physicochemical properties can reveal the evolutionary processes and adaptive changes of viruses
Note: ProtParam software was used for the analysis of physicochemical properties. Significant change threshold: A change exceeding 10% compared to the reference is considered a significant change. "GRAVY" is an abbreviation for "grand average of hydropathicity".

Group Protein name Molecular weight Theoretical PI Extinction coefficients Aliphatic index GRAVY
Mutation ORF1ab_pp1ab 794023.78 6.32 928150 86.92 -0.07
Reference ORF1ab_pp1ab 794057.79 6.32 928150 86.87 -0.07




Alterations in protein stability induced by mutation (20143T>C)

The impact of mutations on protein stability directly or indirectly affects the biological characteristics, adaptability, and transmission capacity of the virus
Note: iMutant 2.0 was utilized to analyze the effects of mutations on protein stability. pH 7 and a temperature of 25°C are employed to replicate the in vitro environment. pH 7.4 and a temperature of 37°C are utilized to simulate the in vivo environment.

Mutation Protein name Mutation type Position ΔDDG Stability pH Temperature Condition
F6715L ORF1ab_pp1ab Point 6715 -1.65 Decrease 7 25 Environment
F6715L ORF1ab_pp1ab Point 6715 -1.49 Decrease 7.4 37 Internal




Impact on protein function induced by mutation (20143T>C)

The impact of mutations on protein function
Note: The MutPred2 software was used to predict the pathogenicity of a mutation and gives the molecular mechanism of pathogenicity. A score above 0.5 indicates an increased likelihood of pathogenicity. "Pr" is the abbreviation for "proportion. P" is the abbreviation for "p-value.

Mutation Protein name Mutation type Score Molecular mechanisms
F6715L ORF1ab_pp1ab Point 0.061 Gain of Helix (Pr = 0.26 | P = 0.10)
Altered Cytoplasmic_loop (Pr = 0.22 | P = 2.7e-03)




Exploring mutation (20143T>C) distribution within intrinsically disordered protein regions

Intrinsically Disordered Proteins (IDPs) which refers to protein regions that have no unique 3D structure. In viral proteins, mutations in the disordered regions s are critical for immune evasion and antibody escape, suggesting potential additional implications for vaccines and monoclonal therapeutic strategies.
Note: The iupred3 software was utilized for analyzing IDPs. A score greater than 0.5 is considered indicative of an IDP. In the plot, "POS" represents the position of the mutation.





Alterations in enzyme cleavage sites induced by mutation (20143T>C)

Exploring the impact of mutations on the cleavage sites of 28 enzymes.
Note: The PeptideCutter software was used for detecting enzymes cleavage sites. The increased enzymes cleavage sites refer to the cleavage sites in the mutated protein that are added compared to the reference protein. Conversely, the decreased enzymes cleavage sites indicate the cleavage sites in the mutated protein that are reduced compared to the reference protein.

Mutation Protein name Genome position Enzyme name Increased cleavage sites Decreased cleavage sites
F6715L ORF1ab_pp1ab 20407 Chymotrypsin-high specificity NA
 ESPFELEDFI (pos: 6715)




Impact of spike protein mutation (20143T>C) on antigenicity and immunogenicity

Investigating the impact of mutations on antigenicity and immunogenicity carries important implications for vaccine design and our understanding of immune responses.
Note: An absolute change greater than 0.0102 (three times the median across sites) in antigenicity score is considered significant. An absolute changegreater than 0.2754 (three times the median across sites) in immunogenicity score is considered significant. The VaxiJen tool was utilized for antigenicity analysis. The IEDB tool was used for immunogenicity analysis. Antigens with a prediction score of more than 0.4 for this tool are considered candidate antigens. MHC I immunogenicity score >0, indicating a higher probability to stimulate an immune response.

Group Protein name Protein region Antigenicity score Immunogenicity score




Impact of mutation (20143T>C) on viral transmissibility by the affinity between RBD and ACE2 receptor

Unraveling the impact of mutations on the interaction between the receptor binding domain (RBD) and ACE2 receptor using deep mutational scanning (DMS) experimental data to gain insights into their effects on viral transmissibility.
Note: The ΔBinding affinity represents the disparity between the binding affinity of a mutation and the reference binding affinity. A positive Δbinding affinity value (Δlog10(KD,app) > 0) signifies an increased affinity between RBD and ACE2 receptor due to the mutation. Conversely, a negative value (Δlog10(KD,app) < 0) indicates a reduced affinity between RBD and ACE2 receptor caused by the mutation. A p-value smaller than 0.05 indicates significance. "Ave mut bind" represents the average binding affinity of this mutation. "Ave ref bind" refers to the average binding affinity at a site without any mutation (reference binding affinity).

;
Mutation Protein name Protein region Mutation Position Ave mut bind Ave ref bind ΔBinding affinity P-value Image


The interface between the receptor binding domain (RBD) and ACE2 receptor is depicted in the crystal structure 6JM0.
Note: The structure 6M0J encompasses the RBD range of 333 to 526. The binding sites (403-406, 408, 417, 439, 445-447, 449, 453, 455-456, 473-478, 484-498, and 500-506) on the RBD that interface with ACE2 are indicated in magenta. The binding sites on the RBD that have been identified through the interface footprints experiment. The ACE2 binding sites within the interface are shown in cyan, representing residues within 5Å proximity to the RBD binding sites. The mutation within the RBD range of 333 to 526 is depicted in red.

        Show as:

        Show interface residues:





Impact of mutation (20143T>C) on immune escape by the affinity between RBD and antibody/serum

By utilizing experimental data from deep mutational scanning (DMS), we can uncover how mutations affect the interaction between the receptor binding domain (RBD) and antibodies/serum. This approach provides valuable insights into strategies for evading the host immune response.
Note: We considered a mutation to mediate strong escape if the escape score exceeded 0.1 (10% of the maximum score of 1). A total of 1,504 antibodies/serum data were collected for this analysis. "Condition name" refers to the name of the antibodies/serum. "Mut escape score" represents the escape score of the mutation in that specific condition. "Avg mut escape score" indicates the average escape score of the mutation site in that condition, considering the occurrence of this mutation and other mutations. Class 1 antibodies bind to an epitope only in the RBD “up” conformation, and are the most abundant. Class 2 antibodies bind to the RBD both in “up” and “down” conformations. Class 3 and class 4 antibodies both bind outside the ACE2 binding site. Class 3 antibodies bind the RBD in both the open and closed conformation, while class 4 antibodies bind only in the open conformation.

Mutation Condition name Condition type Condition subtype Condition year Mut escape score Avg mut escape score




Investigating the co-mutation patterns of mutation (20143T>C) across 2,735 viral lineages

Investigating the co-mutation patterns of SARS-CoV-2 across 2,735 viral lineages to unravel the cooperative effects of different mutations. In biological research, correlation analysis of mutation sites helps us understand whether there is a close relationship or interaction between certain mutations.
Note: The Spearman correlation coefficient is used to calculate the correlation between two mutations within each Pango lineage. Holm–Bonferroni method was used for multiple test adjustment. We retained mutation pairs with correlation values greater than 0.6 or less than -0.6 and Holm–Bonferroni corrected p-values less than 0.05.

Associated mutation ID DNA mutation Mutation type Protein name Protein mutation correlation coefficient Lineage
V6169 2148G>A synonymous_variant ORF1ab_pp1a L716L 6.32e-1 BA.1
V9007 2907T>C synonymous_variant S N969N 6.32e-1 BA.1
V9075 3433T>C synonymous_variant S L1145L 6.32e-1 BA.1
V2082 10609A>G missense_variant ORF1ab_pp1a N3537D 8.15e-1 BA.2
V2207 11249C>T missense_variant ORF1ab_pp1a T3750I 9.31e-1 AY.5
V4842 -5C>T upstream_gene_variant ORF7a None 6.66e-1 AY.5
V5177 236A>G missense_variant ORF8 Y79C 9.44e-1 AY.5
V6247 2637C>T synonymous_variant ORF1ab_pp1a V879V 9.88e-1 AY.5
V6327 3246C>T synonymous_variant ORF1ab_pp1a A1082A 8.78e-1 AY.5
V6913 7827C>T synonymous_variant ORF1ab_pp1a L2609L 9.90e-1 AY.5
V8215 17925C>T synonymous_variant ORF1ab_pp1ab T5975T 9.21e-1 AY.5
V8510 20316G>T synonymous_variant ORF1ab_pp1ab V6772V 9.88e-1 AY.5
V9822 27T>C synonymous_variant ORF10 F9F 9.76e-1 AY.5
V9822 27T>C synonymous_variant ORF10 F9F 7.07e-1 AY.126
V8326 18693T>C synonymous_variant ORF1ab_pp1ab N6231N 1.00e+0 XBB.1.5
V1021 3478C>T missense_variant ORF1ab_pp1a H1160Y 1.00e+0 A
V1191 4574T>C missense_variant ORF1ab_pp1a I1525T 1.00e+0 A
V1241 4790C>T missense_variant ORF1ab_pp1a T1597I 1.00e+0 A
V1319 5383A>C missense_variant ORF1ab_pp1a K1795Q 1.00e+0 A
V1334 5465C>T missense_variant ORF1ab_pp1a T1822I 7.07e-1 A
V142 113T>C missense_variant ORF1ab_pp1a V38A 1.00e+0 A
V1431 6097G>A missense_variant ORF1ab_pp1a A2033T 1.00e+0 A
V1457 6181G>A missense_variant ORF1ab_pp1a V2061I 1.00e+0 A
V256 413C>T missense_variant ORF1ab_pp1a A138V 1.00e+0 A
V268 439G>A missense_variant ORF1ab_pp1a D147N 1.00e+0 A
V2857 16755G>T missense_variant ORF1ab_pp1ab E5585D 7.07e-1 A
V3241 19420G>A missense_variant ORF1ab_pp1ab V6474I 1.00e+0 A
V3824 1037G>C missense_variant S R346T 1.00e+0 A
V4261 3682G>A missense_variant S V1228I 1.00e+0 A
V4341 85G>A missense_variant ORF3a V29I 1.00e+0 A
V460 1249C>T missense_variant ORF1ab_pp1a H417Y 1.00e+0 A
V4634 776T>C missense_variant ORF3a V259A 1.00e+0 A
V4694 215A>G missense_variant E D72G 1.00e+0 A
V4787 562G>T missense_variant M A188S 1.00e+0 A
V4818 85C>T missense_variant ORF6 L29F 1.00e+0 A
V4986 314C>T missense_variant ORF7a A105V 1.00e+0 A
V5043 109C>T missense_variant ORF7b H37Y 1.00e+0 A
V5064 7T>C missense_variant ORF8 F3L 1.00e+0 A
V5203 328G>C missense_variant ORF8 E110Q 1.00e+0 A
V522 1493C>T missense_variant ORF1ab_pp1a A498V 7.07e-1 A
V5235 -8A>T upstream_gene_variant N None 1.00e+0 A
V5236 -5C>T upstream_gene_variant N None 1.00e+0 A
V5325 109T>C missense_variant N S37P 1.00e+0 A
V5455 602G>A missense_variant N S201N 1.00e+0 A
V5729 *4312C>T downstream_gene_variant S None 7.07e-1 A
V58 -76C>T upstream_gene_variant ORF1ab_pp1a None 1.00e+0 A
V5847 81C>T synonymous_variant ORF1ab_pp1a L27L 1.00e+0 A
V5857 114C>T synonymous_variant ORF1ab_pp1a V38V 1.00e+0 A
V5875 222G>T synonymous_variant ORF1ab_pp1a S74S 1.00e+0 A
V5880 246T>C synonymous_variant ORF1ab_pp1a G82G 7.07e-1 A
V5933 540G>A synonymous_variant ORF1ab_pp1a G180G 1.00e+0 A
V5941 570C>T synonymous_variant ORF1ab_pp1a F190F 1.00e+0 A
V5964 687C>T synonymous_variant ORF1ab_pp1a Y229Y 1.00e+0 A
V5974 756G>A synonymous_variant ORF1ab_pp1a Q252Q 1.00e+0 A
V5983 829T>C synonymous_variant ORF1ab_pp1a L277L 1.00e+0 A
V5998 921G>T synonymous_variant ORF1ab_pp1a A307A 1.00e+0 A
V6014 1023C>T synonymous_variant ORF1ab_pp1a C341C 1.00e+0 A
V6020 1078T>C synonymous_variant ORF1ab_pp1a L360L 1.00e+0 A
V6026 1155C>T synonymous_variant ORF1ab_pp1a A385A 1.00e+0 A
V6032 1191T>C synonymous_variant ORF1ab_pp1a L397L 1.00e+0 A
V6036 1215C>T synonymous_variant ORF1ab_pp1a A405A 1.00e+0 A
V6049 1302C>T synonymous_variant ORF1ab_pp1a N434N 1.00e+0 A
V6051 1323A>G synonymous_variant ORF1ab_pp1a E441E 1.00e+0 A
V6052 1329C>T synonymous_variant ORF1ab_pp1a S443S 7.07e-1 A
V6057 1362C>T synonymous_variant ORF1ab_pp1a L454L 1.00e+0 A
V6089 1620T>A synonymous_variant ORF1ab_pp1a A540A 7.07e-1 A
V6093 1638A>T synonymous_variant ORF1ab_pp1a S546S 1.00e+0 A
V6101 1695C>T synonymous_variant ORF1ab_pp1a A565A 1.00e+0 A
V6120 1830G>A synonymous_variant ORF1ab_pp1a S610S 1.00e+0 A
V6134 1884T>C synonymous_variant ORF1ab_pp1a L628L 1.00e+0 A
V6177 2185C>T synonymous_variant ORF1ab_pp1a L729L 1.00e+0 A
V6220 2448A>G synonymous_variant ORF1ab_pp1a K816K 1.00e+0 A
V6222 2466G>A synonymous_variant ORF1ab_pp1a K822K 1.00e+0 A
V6231 2538T>C synonymous_variant ORF1ab_pp1a D846D 1.00e+0 A
V6268 2784T>C synonymous_variant ORF1ab_pp1a D928D 1.00e+0 A
V6314 3168G>A synonymous_variant ORF1ab_pp1a V1056V 7.07e-1 A
V6361 3519C>T synonymous_variant ORF1ab_pp1a V1173V 1.00e+0 A
V6472 4377G>A synonymous_variant ORF1ab_pp1a L1459L 7.07e-1 A
V6491 4545C>T synonymous_variant ORF1ab_pp1a S1515S 1.00e+0 A
V6496 4611C>T synonymous_variant ORF1ab_pp1a Y1537Y 1.00e+0 A
V6499 4623T>C synonymous_variant ORF1ab_pp1a P1541P 1.00e+0 A
V6536 4863A>G synonymous_variant ORF1ab_pp1a L1621L 7.07e-1 A
V6538 4879C>T synonymous_variant ORF1ab_pp1a L1627L 7.07e-1 A
V6552 4953T>C synonymous_variant ORF1ab_pp1a N1651N 1.00e+0 A
V6555 4974C>T synonymous_variant ORF1ab_pp1a Y1658Y 1.00e+0 A
V6565 5040G>A synonymous_variant ORF1ab_pp1a L1680L 1.00e+0 A
V6568 5067G>A synonymous_variant ORF1ab_pp1a K1689K 1.00e+0 A
V6569 5073T>C synonymous_variant ORF1ab_pp1a N1691N 1.00e+0 A
V6571 5083C>T synonymous_variant ORF1ab_pp1a L1695L 1.00e+0 A
V6574 5100C>T synonymous_variant ORF1ab_pp1a Y1700Y 1.00e+0 A
V6580 5157T>C synonymous_variant ORF1ab_pp1a N1719N 1.00e+0 A
V6585 5214T>C synonymous_variant ORF1ab_pp1a H1738H 1.00e+0 A
V6591 5247C>T synonymous_variant ORF1ab_pp1a N1749N 7.07e-1 A
V6598 5283C>T synonymous_variant ORF1ab_pp1a T1761T 1.00e+0 A
V6616 5400G>A synonymous_variant ORF1ab_pp1a Q1800Q 1.00e+0 A
V6627 5508T>C synonymous_variant ORF1ab_pp1a Y1836Y 1.00e+0 A
V6632 5568C>T synonymous_variant ORF1ab_pp1a S1856S 1.00e+0 A
V6645 5679C>T synonymous_variant ORF1ab_pp1a D1893D 1.00e+0 A
V6648 5700T>C synonymous_variant ORF1ab_pp1a Y1900Y 1.00e+0 A
V6649 5709C>T synonymous_variant ORF1ab_pp1a D1903D 1.00e+0 A
V6654 5760T>C synonymous_variant ORF1ab_pp1a Y1920Y 7.07e-1 A
V6658 5778T>C synonymous_variant ORF1ab_pp1a D1926D 7.07e-1 A
V6662 5802T>C synonymous_variant ORF1ab_pp1a N1934N 1.00e+0 A
V6676 5931C>T synonymous_variant ORF1ab_pp1a P1977P 1.00e+0 A
V6680 5961T>C synonymous_variant ORF1ab_pp1a H1987H 1.00e+0 A
V6683 5997T>C synonymous_variant ORF1ab_pp1a N1999N 1.00e+0 A
V6688 6018T>C synonymous_variant ORF1ab_pp1a N2006N 7.07e-1 A
V6689 6021C>T synonymous_variant ORF1ab_pp1a T2007T 1.00e+0 A
V6693 6069T>C synonymous_variant ORF1ab_pp1a N2023N 1.00e+0 A
V6701 6093G>A synonymous_variant ORF1ab_pp1a E2031E 1.00e+0 A
V6743 6384T>A synonymous_variant ORF1ab_pp1a A2128A 1.00e+0 A
V6753 6441C>T synonymous_variant ORF1ab_pp1a N2147N 1.00e+0 A
V6755 6471T>C synonymous_variant ORF1ab_pp1a V2157V 1.00e+0 A
V6765 6585G>T synonymous_variant ORF1ab_pp1a P2195P 1.00e+0 A
V6797 6831T>C synonymous_variant ORF1ab_pp1a T2277T 1.00e+0 A
V6829 7128G>A synonymous_variant ORF1ab_pp1a P2376P 1.00e+0 A
V6836 7170T>C synonymous_variant ORF1ab_pp1a F2390F 1.00e+0 A
V6849 7329C>T synonymous_variant ORF1ab_pp1a G2443G 1.00e+0 A
V6854 7368T>C synonymous_variant ORF1ab_pp1a D2456D 1.00e+0 A
V6881 7590T>C synonymous_variant ORF1ab_pp1a N2530N 1.00e+0 A
V6890 7671G>T synonymous_variant ORF1ab_pp1a A2557A 1.00e+0 A
V6898 7746T>C synonymous_variant ORF1ab_pp1a D2582D 1.00e+0 A
V6932 7977T>C synonymous_variant ORF1ab_pp1a H2659H 1.00e+0 A
V6936 8001C>T synonymous_variant ORF1ab_pp1a G2667G 1.00e+0 A
V6943 8055C>T synonymous_variant ORF1ab_pp1a P2685P 1.00e+0 A
V6945 8061C>T synonymous_variant ORF1ab_pp1a D2687D 7.07e-1 A
V6962 8199T>C synonymous_variant ORF1ab_pp1a A2733A 1.00e+0 A
V6963 8208T>C synonymous_variant ORF1ab_pp1a N2736N 1.00e+0 A
V6965 8214A>G synonymous_variant ORF1ab_pp1a L2738L 1.00e+0 A
V6972 8325A>G synonymous_variant ORF1ab_pp1a K2775K 1.00e+0 A
V6978 8361C>T synonymous_variant ORF1ab_pp1a F2787F 7.07e-1 A
V6982 8397T>C synonymous_variant ORF1ab_pp1a H2799H 1.00e+0 A
V7061 8955G>A synonymous_variant ORF1ab_pp1a R2985R 7.07e-1 A
V7085 9174A>G synonymous_variant ORF1ab_pp1a T3058T 1.00e+0 A
V7090 9189T>C synonymous_variant ORF1ab_pp1a Y3063Y 1.00e+0 A
V7102 9294C>T synonymous_variant ORF1ab_pp1a Y3098Y 7.07e-1 A
V7109 9378T>C synonymous_variant ORF1ab_pp1a I3126I 1.00e+0 A
V7111 9396C>T synonymous_variant ORF1ab_pp1a F3132F 1.00e+0 A
V7116 9459C>T synonymous_variant ORF1ab_pp1a F3153F 1.00e+0 A
V7118 9477T>C synonymous_variant ORF1ab_pp1a N3159N 1.00e+0 A
V7136 9592C>T synonymous_variant ORF1ab_pp1a L3198L 1.00e+0 A
V7149 9666T>C synonymous_variant ORF1ab_pp1a D3222D 1.00e+0 A
V7155 9702C>T synonymous_variant ORF1ab_pp1a L3234L 1.00e+0 A
V7159 9717T>C synonymous_variant ORF1ab_pp1a N3239N 1.00e+0 A
V7168 9765C>T synonymous_variant ORF1ab_pp1a T3255T 1.00e+0 A
V7195 9942C>T synonymous_variant ORF1ab_pp1a N3314N 7.07e-1 A
V7218 10167C>T synonymous_variant ORF1ab_pp1a Y3389Y 1.00e+0 A
V7219 10182G>A synonymous_variant ORF1ab_pp1a R3394R 1.00e+0 A
V7221 10188T>C synonymous_variant ORF1ab_pp1a N3396N 1.00e+0 A
V7222 10191C>T synonymous_variant ORF1ab_pp1a F3397F 1.00e+0 A
V7231 10272C>T synonymous_variant ORF1ab_pp1a Y3424Y 1.00e+0 A
V7232 10278C>T synonymous_variant ORF1ab_pp1a H3426H 1.00e+0 A
V7238 10317C>T synonymous_variant ORF1ab_pp1a D3439D 7.07e-1 A
V7249 10416C>T synonymous_variant ORF1ab_pp1a Y3472Y 1.00e+0 A
V7253 10449C>T synonymous_variant ORF1ab_pp1a L3483L 1.00e+0 A
V7258 10482C>T synonymous_variant ORF1ab_pp1a N3494N 1.00e+0 A
V7263 10521A>G synonymous_variant ORF1ab_pp1a Q3507Q 1.00e+0 A
V7276 10647A>G synonymous_variant ORF1ab_pp1a L3549L 1.00e+0 A
V7281 10689C>T synonymous_variant ORF1ab_pp1a C3563C 7.07e-1 A
V7289 10740C>T synonymous_variant ORF1ab_pp1a H3580H 1.00e+0 A
V7291 10755C>T synonymous_variant ORF1ab_pp1a L3585L 1.00e+0 A
V7293 10785C>T synonymous_variant ORF1ab_pp1a V3595V 1.00e+0 A
V7296 10812T>C synonymous_variant ORF1ab_pp1a F3604F 1.00e+0 A
V7306 10935C>T synonymous_variant ORF1ab_pp1a A3645A 7.07e-1 A
V7352 11385C>T synonymous_variant ORF1ab_pp1a G3795G 1.00e+0 A
V7358 11409C>T synonymous_variant ORF1ab_pp1a Y3803Y 7.07e-1 A
V7369 11487C>T synonymous_variant ORF1ab_pp1a L3829L 1.00e+0 A
V7421 11805G>T synonymous_variant ORF1ab_pp1a L3935L 7.07e-1 A
V7424 11820C>T synonymous_variant ORF1ab_pp1a T3940T 1.00e+0 A
V7426 11835C>T synonymous_variant ORF1ab_pp1a A3945A 1.00e+0 A
V7439 11916T>C synonymous_variant ORF1ab_pp1a D3972D 1.00e+0 A
V7453 12039T>C synonymous_variant ORF1ab_pp1a Y4013Y 7.07e-1 A
V7464 12135C>T synonymous_variant ORF1ab_pp1a L4045L 1.00e+0 A
V7476 12208C>T synonymous_variant ORF1ab_pp1a L4070L 7.07e-1 A
V7496 12468C>T synonymous_variant ORF1ab_pp1a A4156A 1.00e+0 A
V7501 12504G>A synonymous_variant ORF1ab_pp1a A4168A 1.00e+0 A
V7504 12516C>T synonymous_variant ORF1ab_pp1a Y4172Y 7.07e-1 A
V7515 12585A>G synonymous_variant ORF1ab_pp1a R4195R 1.00e+0 A
V7537 12744C>T synonymous_variant ORF1ab_pp1a A4248A 1.00e+0 A
V7538 12754C>T synonymous_variant ORF1ab_pp1a L4252L 7.07e-1 A
V7572 12990C>T synonymous_variant ORF1ab_pp1a C4330C 1.00e+0 A
V7621 13353G>A synonymous_variant ORF1ab_pp1ab K4451K 1.00e+0 A
V7622 13356C>T synonymous_variant ORF1ab_pp1ab D4452D 1.00e+0 A
V7637 13515T>C synonymous_variant ORF1ab_pp1ab H4505H 1.00e+0 A
V7651 13686T>C synonymous_variant ORF1ab_pp1ab D4562D 1.00e+0 A
V7661 13770T>C synonymous_variant ORF1ab_pp1ab N4590N 1.00e+0 A
V7674 13839T>C synonymous_variant ORF1ab_pp1ab D4613D 1.00e+0 A
V7682 13914C>T synonymous_variant ORF1ab_pp1ab T4638T 1.00e+0 A
V7691 13956C>T synonymous_variant ORF1ab_pp1ab D4652D 7.07e-1 A
V7693 13971C>T synonymous_variant ORF1ab_pp1ab Y4657Y 1.00e+0 A
V7696 13998C>T synonymous_variant ORF1ab_pp1ab D4666D 1.00e+0 A
V7731 14241T>C synonymous_variant ORF1ab_pp1ab H4747H 1.00e+0 A
V7797 14667C>T synonymous_variant ORF1ab_pp1ab N4889N 1.00e+0 A
V7800 14676A>G synonymous_variant ORF1ab_pp1ab K4892K 1.00e+0 A
V7827 14952C>T synonymous_variant ORF1ab_pp1ab S4984S 1.00e+0 A
V7834 15009C>T synonymous_variant ORF1ab_pp1ab N5003N 1.00e+0 A
V7837 15033T>C synonymous_variant ORF1ab_pp1ab Y5011Y 1.00e+0 A
V7867 15276C>T synonymous_variant ORF1ab_pp1ab V5092V 7.07e-1 A
V7886 15420T>C synonymous_variant ORF1ab_pp1ab Y5140Y 1.00e+0 A
V7895 15504G>A synonymous_variant ORF1ab_pp1ab V5168V 1.00e+0 A
V7908 15624T>C synonymous_variant ORF1ab_pp1ab H5208H 1.00e+0 A
V7932 15747A>G synonymous_variant ORF1ab_pp1ab E5249E 1.00e+0 A
V7944 15870C>T synonymous_variant ORF1ab_pp1ab H5290H 1.00e+0 A
V7967 16065C>T synonymous_variant ORF1ab_pp1ab Y5355Y 1.00e+0 A
V7970 16098C>T synonymous_variant ORF1ab_pp1ab V5366V 7.07e-1 A
V7972 16110T>C synonymous_variant ORF1ab_pp1ab N5370N 1.00e+0 A
V7990 16215T>C synonymous_variant ORF1ab_pp1ab F5405F 1.00e+0 A
V7995 16275T>C synonymous_variant ORF1ab_pp1ab D5425D 1.00e+0 A
V7998 16290T>C synonymous_variant ORF1ab_pp1ab F5430F 1.00e+0 A
V8013 16392T>C synonymous_variant ORF1ab_pp1ab A5464A 1.00e+0 A
V8021 16464T>C synonymous_variant ORF1ab_pp1ab H5488H 1.00e+0 A
V8025 16503C>T synonymous_variant ORF1ab_pp1ab N5501N 1.00e+0 A
V8064 16815G>A synonymous_variant ORF1ab_pp1ab Q5605Q 1.00e+0 A
V8067 16855C>T synonymous_variant ORF1ab_pp1ab L5619L 1.00e+0 A
V8100 17070G>A synonymous_variant ORF1ab_pp1ab T5690T 1.00e+0 A
V8105 17109C>T synonymous_variant ORF1ab_pp1ab A5703A 1.00e+0 A
V8107 17139C>T synonymous_variant ORF1ab_pp1ab A5713A 1.00e+0 A
V8117 17178T>A synonymous_variant ORF1ab_pp1ab P5726P 1.00e+0 A
V8132 17286C>T synonymous_variant ORF1ab_pp1ab L5762L 1.00e+0 A
V8144 17412C>T synonymous_variant ORF1ab_pp1ab I5804I 1.00e+0 A
V8161 17502C>T synonymous_variant ORF1ab_pp1ab V5834V 1.00e+0 A
V8172 17586C>T synonymous_variant ORF1ab_pp1ab G5862G 1.00e+0 A
V8185 17712C>T synonymous_variant ORF1ab_pp1ab D5904D 7.07e-1 A
V8204 17856C>T synonymous_variant ORF1ab_pp1ab L5952L 1.00e+0 A
V8217 17967T>C synonymous_variant ORF1ab_pp1ab Y5989Y 7.07e-1 A
V8219 17988C>T synonymous_variant ORF1ab_pp1ab N5996N 1.00e+0 A
V8222 18003C>T synonymous_variant ORF1ab_pp1ab R6001R 1.00e+0 A
V8223 18012T>C synonymous_variant ORF1ab_pp1ab A6004A 1.00e+0 A
V8226 18042C>T synonymous_variant ORF1ab_pp1ab F6014F 1.00e+0 A
V8228 18051G>A synonymous_variant ORF1ab_pp1ab E6017E 1.00e+0 A
V8232 18084C>T synonymous_variant ORF1ab_pp1ab T6028T 7.07e-1 A
V8247 18177C>T synonymous_variant ORF1ab_pp1ab S6059S 1.00e+0 A
V8251 18198G>A synonymous_variant ORF1ab_pp1ab P6066P 1.00e+0 A
V8257 18210A>G synonymous_variant ORF1ab_pp1ab Q6070Q 1.00e+0 A
V8259 18219C>T synonymous_variant ORF1ab_pp1ab H6073H 1.00e+0 A
V8260 18222C>T synonymous_variant ORF1ab_pp1ab L6074L 1.00e+0 A
V8261 18237C>T synonymous_variant ORF1ab_pp1ab Y6079Y 1.00e+0 A
V8265 18291C>T synonymous_variant ORF1ab_pp1ab D6097D 7.07e-1 A
V8270 18321A>G synonymous_variant ORF1ab_pp1ab V6107V 1.00e+0 A
V8277 18387G>A synonymous_variant ORF1ab_pp1ab E6129E 1.00e+0 A
V8279 18393C>T synonymous_variant ORF1ab_pp1ab T6131T 1.00e+0 A
V8292 18480C>T synonymous_variant ORF1ab_pp1ab Y6160Y 1.00e+0 A
V8294 18486T>C synonymous_variant ORF1ab_pp1ab Y6162Y 1.00e+0 A
V8295 18492G>A synonymous_variant ORF1ab_pp1ab P6164P 1.00e+0 A
V8300 18540C>T synonymous_variant ORF1ab_pp1ab S6180S 1.00e+0 A
V8302 18549T>C synonymous_variant ORF1ab_pp1ab D6183D 1.00e+0 A
V8303 18550C>T synonymous_variant ORF1ab_pp1ab L6184L 1.00e+0 A
V8316 18621C>T synonymous_variant ORF1ab_pp1ab V6207V 1.00e+0 A
V8321 18663T>C synonymous_variant ORF1ab_pp1ab Y6221Y 1.00e+0 A
V8330 18717C>T synonymous_variant ORF1ab_pp1ab H6239H 1.00e+0 A
V8333 18753C>T synonymous_variant ORF1ab_pp1ab F6251F 1.00e+0 A
V8335 18765C>T synonymous_variant ORF1ab_pp1ab H6255H 7.07e-1 A
V8349 18879T>C synonymous_variant ORF1ab_pp1ab Y6293Y 1.00e+0 A
V8354 18900C>T synonymous_variant ORF1ab_pp1ab D6300D 7.07e-1 A
V8356 18906C>T synonymous_variant ORF1ab_pp1ab F6302F 1.00e+0 A
V8365 18981C>T synonymous_variant ORF1ab_pp1ab D6327D 1.00e+0 A
V8367 18991C>T synonymous_variant ORF1ab_pp1ab L6331L 1.00e+0 A
V8369 18999C>T synonymous_variant ORF1ab_pp1ab N6333N 1.00e+0 A
V8378 19116C>T synonymous_variant ORF1ab_pp1ab Y6372Y 1.00e+0 A
V8379 19119T>C synonymous_variant ORF1ab_pp1ab S6373S 1.00e+0 A
V8390 19212A>G synonymous_variant ORF1ab_pp1ab L6404L 1.00e+0 A
V8403 19320T>C synonymous_variant ORF1ab_pp1ab D6440D 1.00e+0 A
V8404 19326T>C synonymous_variant ORF1ab_pp1ab Y6442Y 1.00e+0 A
V8405 19329C>T synonymous_variant ORF1ab_pp1ab N6443N 1.00e+0 A
V8407 19338C>T synonymous_variant ORF1ab_pp1ab N6446N 1.00e+0 A
V8411 19392G>A synonymous_variant ORF1ab_pp1ab K6464K 1.00e+0 A
V8414 19410A>G synonymous_variant ORF1ab_pp1ab Q6470Q 1.00e+0 A
V8434 19611C>T synonymous_variant ORF1ab_pp1ab I6537I 1.00e+0 A
V8435 19617C>T synonymous_variant ORF1ab_pp1ab D6539D 1.00e+0 A
V8450 19722T>C synonymous_variant ORF1ab_pp1ab F6574F 1.00e+0 A
V8465 19869C>T synonymous_variant ORF1ab_pp1ab A6623A 1.00e+0 A
V8478 20043C>T synonymous_variant ORF1ab_pp1ab G6681G 1.00e+0 A
V8498 20190T>C synonymous_variant ORF1ab_pp1ab Y6730Y 1.00e+0 A
V8499 20193C>T synonymous_variant ORF1ab_pp1ab F6731F 1.00e+0 A
V8504 20256T>C synonymous_variant ORF1ab_pp1ab D6752D 1.00e+0 A
V8507 20280C>T synonymous_variant ORF1ab_pp1ab S6760S 1.00e+0 A
V8518 20406G>A synonymous_variant ORF1ab_pp1ab A6802A 7.07e-1 A
V8522 20439C>T synonymous_variant ORF1ab_pp1ab Y6813Y 1.00e+0 A
V8531 20532A>G synonymous_variant ORF1ab_pp1ab K6844K 1.00e+0 A
V8537 20586T>C synonymous_variant ORF1ab_pp1ab N6862N 1.00e+0 A
V8563 20790C>T synonymous_variant ORF1ab_pp1ab Y6930Y 1.00e+0 A
V8564 20793C>T synonymous_variant ORF1ab_pp1ab D6931D 7.07e-1 A
V8571 20880T>C synonymous_variant ORF1ab_pp1ab A6960A 1.00e+0 A
V8574 20895G>A synonymous_variant ORF1ab_pp1ab V6965V 1.00e+0 A
V8588 20970C>T synonymous_variant ORF1ab_pp1ab A6990A 1.00e+0 A
V8590 20991G>A synonymous_variant ORF1ab_pp1ab A6997A 1.00e+0 A
V8601 21042C>T synonymous_variant ORF1ab_pp1ab R7014R 1.00e+0 A
V8604 21093T>C synonymous_variant ORF1ab_pp1ab N7031N 1.00e+0 A
V8609 21144T>C synonymous_variant ORF1ab_pp1ab F7048F 1.00e+0 A
V8611 21153A>G synonymous_variant ORF1ab_pp1ab K7051K 1.00e+0 A
V8616 21249C>T synonymous_variant ORF1ab_pp1ab N7083N 1.00e+0 A
V8620 21285C>T synonymous_variant ORF1ab_pp1ab N7095N 1.00e+0 A
V869 2945A>G missense_variant ORF1ab_pp1a D982G 1.00e+0 A
V8744 870C>T synonymous_variant S D290D 1.00e+0 A
V8746 882C>T synonymous_variant S D294D 7.07e-1 A
V8747 888C>T synonymous_variant S L296L 1.00e+0 A
V8750 915C>T synonymous_variant S S305S 1.00e+0 A
V8751 918C>T synonymous_variant S F306F 1.00e+0 A
V8753 936C>T synonymous_variant S I312I 1.00e+0 A
V8764 1038A>G synonymous_variant S R346R 1.00e+0 A
V8767 1065G>A synonymous_variant S R355R 1.00e+0 A
V8786 1230C>T synonymous_variant S I410I 1.00e+0 A
V8789 1239G>A synonymous_variant S G413G 1.00e+0 A
V8815 1473T>C synonymous_variant S P491P 1.00e+0 A
V8820 1497C>T synonymous_variant S P499P 1.00e+0 A
V8822 1515C>T synonymous_variant S Y505Y 1.00e+0 A
V8831 1608C>T synonymous_variant S N536N 1.00e+0 A
V8836 1629C>T synonymous_variant S F543F 1.00e+0 A
V8837 1641A>G synonymous_variant S T547T 1.00e+0 A
V8843 1686C>T synonymous_variant S F562F 1.00e+0 A
V8844 1698C>T synonymous_variant S G566G 1.00e+0 A
V8868 1872T>C synonymous_variant S I624I 1.00e+0 A
V8869 1881T>C synonymous_variant S D627D 1.00e+0 A
V8872 1908T>C synonymous_variant S Y636Y 1.00e+0 A
V8880 1968C>T synonymous_variant S V656V 1.00e+0 A
V8881 1971C>T synonymous_variant S N657N 1.00e+0 A
V8883 1977A>G synonymous_variant S S659S 1.00e+0 A
V8887 1995C>T synonymous_variant S P665P 1.00e+0 A
V8889 2004A>T synonymous_variant S A668A 1.00e+0 A
V8894 2031G>A synonymous_variant S Q677Q 1.00e+0 A
V8903 2076C>T synonymous_variant S I692I 7.07e-1 A
V8909 2145C>T synonymous_variant S P715P 1.00e+0 A
V8915 2196C>T synonymous_variant S T732T 1.00e+0 A
V8916 2205A>G synonymous_variant S S735S 1.00e+0 A
V8921 2287T>C synonymous_variant S L763L 1.00e+0 A
V8942 2457A>G synonymous_variant S E819E 1.00e+0 A
V8943 2460T>C synonymous_variant S D820D 1.00e+0 A
V8960 2547C>T synonymous_variant S L849L 1.00e+0 A
V8964 2568C>T synonymous_variant S N856N 7.07e-1 A
V8990 2802T>C synonymous_variant S I934I 1.00e+0 A
V8991 2808C>T synonymous_variant S D936D 1.00e+0 A
V8994 2820C>T synonymous_variant S S940S 1.00e+0 A
V8997 2853G>T synonymous_variant S V951V 1.00e+0 A
V9007 2907T>C synonymous_variant S N969N 1.00e+0 A
V9026 3135G>A synonymous_variant S K1045K 1.00e+0 A
V9029 3144T>C synonymous_variant S H1048H 1.00e+0 A
V9034 3183C>T synonymous_variant S V1061V 1.00e+0 A
V9046 3234T>C synonymous_variant S A1078A 1.00e+0 A
V9055 3276A>G synonymous_variant S E1092E 1.00e+0 A
V9056 3282C>T synonymous_variant S V1094V 1.00e+0 A
V9058 3303C>T synonymous_variant S H1101H 1.00e+0 A
V9074 3429T>A synonymous_variant S P1143P 1.00e+0 A
V9075 3433T>C synonymous_variant S L1145L 1.00e+0 A
V9076 3438C>T synonymous_variant S D1146D 7.07e-1 A
V9077 3441A>G synonymous_variant S S1147S 1.00e+0 A
V908 3055G>A missense_variant ORF1ab_pp1a V1019I 1.00e+0 A
V9082 3456A>G synonymous_variant S L1152L 1.00e+0 A
V9089 3510T>C synonymous_variant S S1170S 1.00e+0 A
V9091 3516T>C synonymous_variant S I1172I 1.00e+0 A
V9095 3534C>T synonymous_variant S N1178N 1.00e+0 A
V9097 3561T>C synonymous_variant S N1187N 1.00e+0 A
V9099 3577T>C synonymous_variant S L1193L 1.00e+0 A
V9106 3597T>C synonymous_variant S D1199D 1.00e+0 A
V9112 3645C>T synonymous_variant S Y1215Y 1.00e+0 A
V9117 3690G>T synonymous_variant S V1230V 1.00e+0 A
V9120 3714C>T synonymous_variant S T1238T 1.00e+0 A
V9123 3753A>G synonymous_variant S G1251G 1.00e+0 A
V9138 21C>T synonymous_variant ORF3a I7I 1.00e+0 A
V9141 60C>T synonymous_variant ORF3a I20I 7.07e-1 A
V9165 171G>A synonymous_variant ORF3a Q57Q 1.00e+0 A
V9176 222C>T synonymous_variant ORF3a S74S 1.00e+0 A
V9209 462C>T synonymous_variant ORF3a Y154Y 1.00e+0 A
V9227 630C>T synonymous_variant ORF3a D210D 1.00e+0 A
V9271 87T>C synonymous_variant E V29V 1.00e+0 A
V9276 165T>C synonymous_variant E S55S 1.00e+0 A
V9297 87T>C synonymous_variant M L29L 1.00e+0 A
V9316 231C>T synonymous_variant M T77T 1.00e+0 A
V9341 363C>T synonymous_variant M N121N 1.00e+0 A
V9353 405A>G synonymous_variant M E135E 7.07e-1 A
V9361 444T>C synonymous_variant M H148H 1.00e+0 A
V9365 465T>C synonymous_variant M H155H 1.00e+0 A
V9369 483C>T synonymous_variant M I161I 1.00e+0 A
V9377 531T>C synonymous_variant M S177S 1.00e+0 A
V9379 543G>A synonymous_variant M L181L 1.00e+0 A
V9384 570C>T synonymous_variant M D190D 1.00e+0 A
V9387 606C>A synonymous_variant M G202G 1.00e+0 A
V9404 84T>C synonymous_variant ORF6 N28N 1.00e+0 A
V9446 156C>T synonymous_variant ORF7a N52N 1.00e+0 A
V9452 183T>C synonymous_variant ORF7a T61T 1.00e+0 A
V9477 297A>T synonymous_variant ORF7a P99P 1.00e+0 A
V9528 138T>C synonymous_variant ORF8 Y46Y 1.00e+0 A
V9589 123G>T synonymous_variant N R41R 1.00e+0 A
V9590 126C>T synonymous_variant N P42P 1.00e+0 A
V9633 384C>T synonymous_variant N D128D 7.07e-1 A
V9644 432T>C synonymous_variant N D144D 1.00e+0 A
V9666 522A>G synonymous_variant N E174E 1.00e+0 A
V9667 525G>A synonymous_variant N G175G 1.00e+0 A
V9669 531A>G synonymous_variant N R177R 1.00e+0 A
V9673 546C>T synonymous_variant N A182A 1.00e+0 A
V9683 615T>C synonymous_variant N T205T 1.00e+0 A
V9712 771G>A synonymous_variant N K257K 1.00e+0 A
V9747 924C>T synonymous_variant N A308A 1.00e+0 A
V975 3304A>G missense_variant ORF1ab_pp1a S1102G 1.00e+0 A
V9771 999C>T synonymous_variant N Y333Y 1.00e+0 A
V9773 1011C>T synonymous_variant N I337I 7.07e-1 A
V9791 1122G>A synonymous_variant N K374K 1.00e+0 A
V9813 1245C>T synonymous_variant N D415D 1.00e+0 A
V3245 19426G>A missense_variant ORF1ab_pp1ab V6476I 1.00e+0 AY.112
V1729 7853C>T missense_variant ORF1ab_pp1a A2618V 7.07e-1 AY.121
V2917 17138C>T missense_variant ORF1ab_pp1ab A5713V 7.07e-1 AY.121
V5312 95G>A missense_variant N R32H 9.13e-1 AY.27
V780 2582C>T missense_variant ORF1ab_pp1a T861I 1.00e+0 AY.27
V2207 11249C>T missense_variant ORF1ab_pp1a T3750I 8.16e-1 AY.46.4
V5177 236A>G missense_variant ORF8 Y79C 1.00e+0 AY.46.4
V6327 3246C>T synonymous_variant ORF1ab_pp1a A1082A 8.16e-1 AY.46.4
V6891 7680C>T synonymous_variant ORF1ab_pp1a Y2560Y 1.00e+0 AY.46.4
V6913 7827C>T synonymous_variant ORF1ab_pp1a L2609L 7.07e-1 AY.46.4
V8215 17925C>T synonymous_variant ORF1ab_pp1ab T5975T 1.00e+0 AY.46.4
V8510 20316G>T synonymous_variant ORF1ab_pp1ab V6772V 8.16e-1 AY.46.4
V9066 3366G>T synonymous_variant S V1122V 6.32e-1 AY.46.4
V9822 27T>C synonymous_variant ORF10 F9F 1.00e+0 AY.46.4
V2233 11344G>A missense_variant ORF1ab_pp1a V3782I 1.00e+0 AY.46
V8490 20133G>A synonymous_variant ORF1ab_pp1ab K6711K 7.07e-1 AY.46
V1336 5482A>G missense_variant ORF1ab_pp1a T1828A 7.07e-1 AY.4.8
V7649 13665T>C synonymous_variant ORF1ab_pp1ab Y4555Y 7.07e-1 AY.4.8
V8363 18957T>C synonymous_variant ORF1ab_pp1ab A6319A 1.00e+0 AY.4.8
V2207 11249C>T missense_variant ORF1ab_pp1a T3750I 7.07e-1 AY.5.4
V3794 784G>T missense_variant S A262S 1.00e+0 AY.5.4
V5177 236A>G missense_variant ORF8 Y79C 1.00e+0 AY.5.4
V6247 2637C>T synonymous_variant ORF1ab_pp1a V879V 1.00e+0 AY.5.4
V6327 3246C>T synonymous_variant ORF1ab_pp1a A1082A 1.00e+0 AY.5.4
V6913 7827C>T synonymous_variant ORF1ab_pp1a L2609L 7.07e-1 AY.5.4
V8215 17925C>T synonymous_variant ORF1ab_pp1ab T5975T 1.00e+0 AY.5.4
V9822 27T>C synonymous_variant ORF10 F9F 1.00e+0 AY.5.4
V1985 9808G>A missense_variant ORF1ab_pp1a A3270T 1.00e+0 AY.62
V2143 10957G>T missense_variant ORF1ab_pp1a V3653F 1.00e+0 AY.62
V3560 94T>C missense_variant S F32L 1.00e+0 AY.62
V3665 458T>C missense_variant S M153T 1.00e+0 AY.62
V3674 470T>C missense_variant S F157S 1.00e+0 AY.62
V3741 643G>T missense_variant S D215Y 1.00e+0 AY.62
V4721 11C>T missense_variant M S4F 1.00e+0 AY.62
V4781 463C>T missense_variant M H155Y 7.07e-1 AY.62
V5023 40_42delTTA conservative_inframe_deletion ORF7b L14del 1.00e+0 AY.62
V5025 42A>T missense_variant ORF7b L14F 1.00e+0 AY.62
V5243 -2A>T upstream_gene_variant N None 1.00e+0 AY.62
V5461 608G>A missense_variant N R203K 1.00e+0 AY.62
V5491 637A>T missense_variant N N213Y 1.00e+0 AY.62
V6546 4927C>T synonymous_variant ORF1ab_pp1a L1643L 1.00e+0 AY.62
V9446 156C>T synonymous_variant ORF7a N52N 7.07e-1 AY.62
V9589 123G>T synonymous_variant N R41R 1.00e+0 AY.62
V1201 4625C>T missense_variant ORF1ab_pp1a T1542I 8.16e-1 B.1.1.25
V1334 5465C>T missense_variant ORF1ab_pp1a T1822I 7.06e-1 B.1.1.25
V1951 9428C>T missense_variant ORF1ab_pp1a A3143V 1.00e+0 B.1.1.25
V2688 15142G>T missense_variant ORF1ab_pp1ab A5048S 8.94e-1 B.1.1.25
V2760 15899C>T missense_variant ORF1ab_pp1ab T5300I 1.00e+0 B.1.1.25
V3739 643G>C missense_variant S D215H 8.66e-1 B.1.1.25
V3909 1450G>A missense_variant S E484K 6.32e-1 B.1.1.25
V4177 3233C>T missense_variant S A1078V 1.00e+0 B.1.1.25
V454 1208C>T missense_variant ORF1ab_pp1a T403I 6.32e-1 B.1.1.25
V4990 329T>C missense_variant ORF7a I110T 1.00e+0 B.1.1.25
V6291 2985G>A synonymous_variant ORF1ab_pp1a E995E 1.00e+0 B.1.1.25
V7348 11355C>T synonymous_variant ORF1ab_pp1a F3785F 8.16e-1 B.1.1.25
V9567 48G>A synonymous_variant N T16T 1.00e+0 B.1.1.25
V964 3277A>G missense_variant ORF1ab_pp1a T1093A 8.16e-1 B.1.1.25
V8744 870C>T synonymous_variant S D290D 1.00e+0 B.1.1.269
V7043 8865G>T synonymous_variant ORF1ab_pp1a V2955V 9.72e-1 B.1.1.37
V7918 15675T>C synonymous_variant ORF1ab_pp1ab D5225D 9.81e-1 B.1.1.37
V4343 88C>T missense_variant ORF3a R30C 8.66e-1 B.1.1.519
V2189 11153T>C missense_variant ORF1ab_pp1a V3718A 1.00e+0 B.1.160
V8347 18873A>G synonymous_variant ORF1ab_pp1ab L6291L 1.00e+0 B.1.36
V4586 650C>T missense_variant ORF3a T217I 7.07e-1 B.1.426
V7251 10437C>T synonymous_variant ORF1ab_pp1a D3479D 6.32e-1 B.1.426
V8781 1182T>C synonymous_variant S N394N 1.00e+0 B.1.426
V2187 11152G>A missense_variant ORF1ab_pp1a V3718I 7.07e-1 B.1.526
V4975 289T>C missense_variant ORF7a Y97H 1.00e+0 B.1.526
V8530 20526C>T synonymous_variant ORF1ab_pp1ab V6842V 1.00e+0 B.1.526
V4088 2464C>T missense_variant S L822F 1.00e+0 B.1.619
V5691 23C>T missense_variant ORF10 A8V 1.00e+0 B.1.619
V1163 4391G>A missense_variant ORF1ab_pp1a R1464Q 7.07e-1 BA.1.1.14
V7897 15510C>T synonymous_variant ORF1ab_pp1ab S5170S 8.16e-1 BA.1.1.14
V8991 2808C>T synonymous_variant S D936D 8.16e-1 BA.2.3.13
V6777 6703C>T synonymous_variant ORF1ab_pp1a L2235L 8.64e-1 BA.2.3.18
V2616 14357C>T missense_variant ORF1ab_pp1ab T4786M 7.74e-1 BA.2.3.2
V4633 775G>T missense_variant ORF3a V259L 8.16e-1 BA.2.3.2
V5119 133T>C missense_variant ORF8 W45R 1.00e+0 BA.2.3.2
V6994 8505C>T synonymous_variant ORF1ab_pp1a D2835D 7.74e-1 BA.2.3.2
V4281 3754T>C missense_variant S S1252P 9.64e-1 BA.2.38
V1459 6184C>T missense_variant ORF1ab_pp1a L2062F 1.00e+0 BA.2.62
V2082 10609A>G missense_variant ORF1ab_pp1a N3537D 1.00e+0 BA.2.62
V4723 20C>T missense_variant M T7I 1.00e+0 BA.2.62
V5416 532G>A missense_variant N G178S 7.07e-1 BA.4
V8827 1575T>C synonymous_variant S C525C 7.07e-1 BA.4
V2610 14316G>T missense_variant ORF1ab_pp1ab M4772I 1.00e+0 BA.5.1.6
V8142 17400T>C synonymous_variant ORF1ab_pp1ab Y5800Y 1.00e+0 BA.5.2.48
V1069 3674G>A missense_variant ORF1ab_pp1a R1225K 1.00e+0 B
V1217 4697G>A missense_variant ORF1ab_pp1a R1566K 8.16e-1 B
V1319 5383A>C missense_variant ORF1ab_pp1a K1795Q 8.16e-1 B
V142 113T>C missense_variant ORF1ab_pp1a V38A 1.00e+0 B
V1424 6077A>G missense_variant ORF1ab_pp1a D2026G 1.00e+0 B
V1431 6097G>A missense_variant ORF1ab_pp1a A2033T 1.00e+0 B
V1457 6181G>A missense_variant ORF1ab_pp1a V2061I 1.00e+0 B
V3275 19697C>T missense_variant ORF1ab_pp1ab T6566M 8.16e-1 B
V3294 19783A>G missense_variant ORF1ab_pp1ab I6595V 1.00e+0 B
V3512 21259G>A missense_variant ORF1ab_pp1ab V7087I 1.00e+0 B
V393 998C>T missense_variant ORF1ab_pp1a T333M 8.16e-1 B
V4069 2314G>A missense_variant S V772I 6.32e-1 B
V4097 2521C>T missense_variant S L841F 1.00e+0 B
V4099 2530A>G missense_variant S I844V 1.00e+0 B
V4100 2533G>T missense_variant S A845S 7.07e-1 B
V4454 280C>T missense_variant ORF3a L94F 1.00e+0 B
V4577 628G>T missense_variant ORF3a D210Y 8.16e-1 B
V4634 776T>C missense_variant ORF3a V259A 1.00e+0 B
V4994 346C>T missense_variant ORF7a L116F 8.16e-1 B
V5199 316G>C missense_variant ORF8 E106Q 6.32e-1 B
V521 1492G>A missense_variant ORF1ab_pp1a A498T 1.00e+0 B
V5260 23A>G missense_variant N N8S 1.00e+0 B
V5325 109T>C missense_variant N S37P 6.32e-1 B
V58 -76C>T upstream_gene_variant ORF1ab_pp1a None 1.00e+0 B
V5807 *4385C>T downstream_gene_variant S None 7.07e-1 B
V5829 *4453C>T downstream_gene_variant S None 1.00e+0 B
V5857 114C>T synonymous_variant ORF1ab_pp1a V38V 1.00e+0 B
V5880 246T>C synonymous_variant ORF1ab_pp1a G82G 1.00e+0 B
V5885 264G>A synonymous_variant ORF1ab_pp1a L88L 1.00e+0 B
V5920 441C>T synonymous_variant ORF1ab_pp1a D147D 8.16e-1 B
V5929 510C>T synonymous_variant ORF1ab_pp1a T170T 1.00e+0 B
V5932 534C>T synonymous_variant ORF1ab_pp1a N178N 8.16e-1 B
V5955 655C>T synonymous_variant ORF1ab_pp1a L219L 1.00e+0 B
V5980 822A>G synonymous_variant ORF1ab_pp1a V274V 1.00e+0 B
V5983 829T>C synonymous_variant ORF1ab_pp1a L277L 1.00e+0 B
V5988 861G>A synonymous_variant ORF1ab_pp1a R287R 1.00e+0 B
V5990 885C>T synonymous_variant ORF1ab_pp1a G295G 6.32e-1 B
V5998 921G>T synonymous_variant ORF1ab_pp1a A307A 1.00e+0 B
V6013 1017C>T synonymous_variant ORF1ab_pp1a A339A 1.00e+0 B
V6014 1023C>T synonymous_variant ORF1ab_pp1a C341C 7.07e-1 B
V6020 1078T>C synonymous_variant ORF1ab_pp1a L360L 1.00e+0 B
V6036 1215C>T synonymous_variant ORF1ab_pp1a A405A 1.00e+0 B
V6045 1284C>T synonymous_variant ORF1ab_pp1a S428S 8.16e-1 B
V6051 1323A>G synonymous_variant ORF1ab_pp1a E441E 8.16e-1 B
V6052 1329C>T synonymous_variant ORF1ab_pp1a S443S 6.32e-1 B
V6054 1344C>T synonymous_variant ORF1ab_pp1a D448D 1.00e+0 B
V6056 1350T>C synonymous_variant ORF1ab_pp1a L450L 1.00e+0 B
V6058 1374A>G synonymous_variant ORF1ab_pp1a K458K 1.00e+0 B
V6092 1635A>G synonymous_variant ORF1ab_pp1a R545R 8.16e-1 B
V6101 1695C>T synonymous_variant ORF1ab_pp1a A565A 6.32e-1 B
V6102 1708C>T synonymous_variant ORF1ab_pp1a L570L 8.16e-1 B
V6120 1830G>A synonymous_variant ORF1ab_pp1a S610S 1.00e+0 B
V6144 1962C>T synonymous_variant ORF1ab_pp1a T654T 1.00e+0 B
V6151 2016G>A synonymous_variant ORF1ab_pp1a K672K 1.00e+0 B
V6164 2133G>A synonymous_variant ORF1ab_pp1a T711T 1.00e+0 B
V6177 2185C>T synonymous_variant ORF1ab_pp1a L729L 8.16e-1 B
V6182 2220C>T synonymous_variant ORF1ab_pp1a I740I 1.00e+0 B
V6192 2268T>C synonymous_variant ORF1ab_pp1a V756V 1.00e+0 B
V6205 2379C>T synonymous_variant ORF1ab_pp1a I793I 1.00e+0 B
V6208 2388A>G synonymous_variant ORF1ab_pp1a T796T 1.00e+0 B
V6219 2445C>T synonymous_variant ORF1ab_pp1a L815L 8.16e-1 B
V6222 2466G>A synonymous_variant ORF1ab_pp1a K822K 1.00e+0 B
V6229 2523C>T synonymous_variant ORF1ab_pp1a I841I 1.00e+0 B
V6244 2613C>T synonymous_variant ORF1ab_pp1a F871F 8.16e-1 B
V6245 2616C>T synonymous_variant ORF1ab_pp1a A872A 1.00e+0 B
V6248 2649G>A synonymous_variant ORF1ab_pp1a L883L 1.00e+0 B
V6273 2826G>A synonymous_variant ORF1ab_pp1a E942E 1.00e+0 B
V6296 3024T>C synonymous_variant ORF1ab_pp1a V1008V 8.16e-1 B
V6316 3177T>C synonymous_variant ORF1ab_pp1a N1059N 1.00e+0 B
V6324 3222C>T synonymous_variant ORF1ab_pp1a A1074A 6.32e-1 B
V6369 3573G>A synonymous_variant ORF1ab_pp1a L1191L 1.00e+0 B
V6371 3609C>T synonymous_variant ORF1ab_pp1a I1203I 7.07e-1 B
V6384 3747C>T synonymous_variant ORF1ab_pp1a L1249L 1.00e+0 B
V6386 3756C>T synonymous_variant ORF1ab_pp1a N1252N 8.16e-1 B
V6391 3792T>C synonymous_variant ORF1ab_pp1a H1264H 7.07e-1 B
V6394 3804C>T synonymous_variant ORF1ab_pp1a A1268A 6.32e-1 B
V6410 3924C>T synonymous_variant ORF1ab_pp1a G1308G 1.00e+0 B
V6411 3927T>C synonymous_variant ORF1ab_pp1a T1309T 1.00e+0 B
V6415 3969C>T synonymous_variant ORF1ab_pp1a D1323D 8.16e-1 B
V6422 4011C>T synonymous_variant ORF1ab_pp1a Y1337Y 6.32e-1 B
V6423 4020G>A synonymous_variant ORF1ab_pp1a E1340E 1.00e+0 B
V6428 4066C>T synonymous_variant ORF1ab_pp1a L1356L 7.07e-1 B
V6440 4158C>T synonymous_variant ORF1ab_pp1a R1386R 8.16e-1 B
V6445 4179G>T synonymous_variant ORF1ab_pp1a V1393V 8.16e-1 B
V6446 4191C>T synonymous_variant ORF1ab_pp1a A1397A 8.16e-1 B
V6447 4218T>C synonymous_variant ORF1ab_pp1a Y1406Y 1.00e+0 B
V6452 4269C>T synonymous_variant ORF1ab_pp1a Y1423Y 8.16e-1 B
V6455 4296G>A synonymous_variant ORF1ab_pp1a A1432A 8.16e-1 B
V6463 4321C>T synonymous_variant ORF1ab_pp1a L1441L 7.07e-1 B
V6467 4368C>T synonymous_variant ORF1ab_pp1a G1456G 8.16e-1 B
V6475 4401A>G synonymous_variant ORF1ab_pp1a R1467R 7.07e-1 B
V6480 4455G>A synonymous_variant ORF1ab_pp1a A1485A 1.00e+0 B
V6491 4545C>T synonymous_variant ORF1ab_pp1a S1515S 1.00e+0 B
V6496 4611C>T synonymous_variant ORF1ab_pp1a Y1537Y 7.07e-1 B
V6497 4617T>C synonymous_variant ORF1ab_pp1a S1539S 1.00e+0 B
V6520 4743G>A synonymous_variant ORF1ab_pp1a T1581T 1.00e+0 B
V6536 4863A>G synonymous_variant ORF1ab_pp1a L1621L 1.00e+0 B
V6538 4879C>T synonymous_variant ORF1ab_pp1a L1627L 7.07e-1 B
V6552 4953T>C synonymous_variant ORF1ab_pp1a N1651N 8.16e-1 B
V6555 4974C>T synonymous_variant ORF1ab_pp1a Y1658Y 6.32e-1 B
V6565 5040G>A synonymous_variant ORF1ab_pp1a L1680L 8.16e-1 B
V6568 5067G>A synonymous_variant ORF1ab_pp1a K1689K 1.00e+0 B
V6569 5073T>C synonymous_variant ORF1ab_pp1a N1691N 8.16e-1 B
V6571 5083C>T synonymous_variant ORF1ab_pp1a L1695L 1.00e+0 B
V6575 5107A>C synonymous_variant ORF1ab_pp1a R1703R 1.00e+0 B
V6578 5142C>T synonymous_variant ORF1ab_pp1a I1714I 1.00e+0 B
V6580 5157T>C synonymous_variant ORF1ab_pp1a N1719N 1.00e+0 B
V6583 5202C>T synonymous_variant ORF1ab_pp1a Y1734Y 8.16e-1 B
V6591 5247C>T synonymous_variant ORF1ab_pp1a N1749N 6.32e-1 B
V6598 5283C>T synonymous_variant ORF1ab_pp1a T1761T 1.00e+0 B
V6616 5400G>A synonymous_variant ORF1ab_pp1a Q1800Q 8.16e-1 B
V6627 5508T>C synonymous_variant ORF1ab_pp1a Y1836Y 8.16e-1 B
V6632 5568C>T synonymous_variant ORF1ab_pp1a S1856S 7.07e-1 B
V6649 5709C>T synonymous_variant ORF1ab_pp1a D1903D 1.00e+0 B
V6652 5730A>G synonymous_variant ORF1ab_pp1a Q1910Q 1.00e+0 B
V6654 5760T>C synonymous_variant ORF1ab_pp1a Y1920Y 1.00e+0 B
V6662 5802T>C synonymous_variant ORF1ab_pp1a N1934N 1.00e+0 B
V6666 5880C>T synonymous_variant ORF1ab_pp1a F1960F 7.07e-1 B
V6676 5931C>T synonymous_variant ORF1ab_pp1a P1977P 1.00e+0 B
V6680 5961T>C synonymous_variant ORF1ab_pp1a H1987H 1.00e+0 B
V6683 5997T>C synonymous_variant ORF1ab_pp1a N1999N 1.00e+0 B
V6684 6003C>T synonymous_variant ORF1ab_pp1a A2001A 1.00e+0 B
V6688 6018T>C synonymous_variant ORF1ab_pp1a N2006N 1.00e+0 B
V6693 6069T>C synonymous_variant ORF1ab_pp1a N2023N 1.00e+0 B
V6701 6093G>A synonymous_variant ORF1ab_pp1a E2031E 8.16e-1 B
V6719 6168C>T synonymous_variant ORF1ab_pp1a T2056T 1.00e+0 B
V6728 6264A>G synonymous_variant ORF1ab_pp1a E2088E 1.00e+0 B
V6746 6399C>T synonymous_variant ORF1ab_pp1a V2133V 1.00e+0 B
V6753 6441C>T synonymous_variant ORF1ab_pp1a N2147N 6.32e-1 B
V6755 6471T>C synonymous_variant ORF1ab_pp1a V2157V 1.00e+0 B
V6770 6618C>T synonymous_variant ORF1ab_pp1a V2206V 1.00e+0 B
V6777 6703C>T synonymous_variant ORF1ab_pp1a L2235L 1.00e+0 B
V6817 7002C>T synonymous_variant ORF1ab_pp1a F2334F 8.16e-1 B
V6826 7092T>C synonymous_variant ORF1ab_pp1a L2364L 1.00e+0 B
V6829 7128G>A synonymous_variant ORF1ab_pp1a P2376P 1.00e+0 B
V6836 7170T>C synonymous_variant ORF1ab_pp1a F2390F 1.00e+0 B
V6842 7263C>T synonymous_variant ORF1ab_pp1a V2421V 7.07e-1 B
V6849 7329C>T synonymous_variant ORF1ab_pp1a G2443G 1.00e+0 B
V6852 7344C>T synonymous_variant ORF1ab_pp1a H2448H 7.07e-1 B
V6854 7368T>C synonymous_variant ORF1ab_pp1a D2456D 8.16e-1 B
V6878 7575C>T synonymous_variant ORF1ab_pp1a D2525D 8.16e-1 B
V6898 7746T>C synonymous_variant ORF1ab_pp1a D2582D 1.00e+0 B
V6913 7827C>T synonymous_variant ORF1ab_pp1a L2609L 6.32e-1 B
V6927 7911T>C synonymous_variant ORF1ab_pp1a A2637A 1.00e+0 B
V6928 7914G>A synonymous_variant ORF1ab_pp1a R2638R 1.00e+0 B
V693 2167T>C missense_variant ORF1ab_pp1a S723P 1.00e+0 B
V6962 8199T>C synonymous_variant ORF1ab_pp1a A2733A 1.00e+0 B
V7015 8613C>T synonymous_variant ORF1ab_pp1a G2871G 1.00e+0 B
V7017 8622A>G synonymous_variant ORF1ab_pp1a L2874L 7.07e-1 B
V7034 8805T>C synonymous_variant ORF1ab_pp1a D2935D 1.00e+0 B
V7109 9378T>C synonymous_variant ORF1ab_pp1a I3126I 1.00e+0 B
V7173 9783T>C synonymous_variant ORF1ab_pp1a V3261V 1.00e+0 B
V7185 9891C>T synonymous_variant ORF1ab_pp1a D3297D 8.16e-1 B
V721 2269G>A missense_variant ORF1ab_pp1a V757I 1.00e+0 B
V7220 10185C>T synonymous_variant ORF1ab_pp1a P3395P 6.32e-1 B
V7243 10359A>G synonymous_variant ORF1ab_pp1a T3453T 1.00e+0 B
V7286 10725A>G synonymous_variant ORF1ab_pp1a T3575T 1.00e+0 B
V7291 10755C>T synonymous_variant ORF1ab_pp1a L3585L 7.07e-1 B
V7293 10785C>T synonymous_variant ORF1ab_pp1a V3595V 7.07e-1 B
V7296 10812T>C synonymous_variant ORF1ab_pp1a F3604F 1.00e+0 B
V7306 10935C>T synonymous_variant ORF1ab_pp1a A3645A 1.00e+0 B
V7331 11190C>T synonymous_variant ORF1ab_pp1a A3730A 8.16e-1 B
V7360 11439C>T synonymous_variant ORF1ab_pp1a Y3813Y 6.32e-1 B
V7361 11454G>A synonymous_variant ORF1ab_pp1a Q3818Q 1.00e+0 B
V7362 11463A>G synonymous_variant ORF1ab_pp1a R3821R 1.00e+0 B
V7381 11547C>T synonymous_variant ORF1ab_pp1a G3849G 1.00e+0 B
V7382 11559C>T synonymous_variant ORF1ab_pp1a I3853I 6.32e-1 B
V739 2327C>T missense_variant ORF1ab_pp1a A776V 7.07e-1 B
V7391 11637C>T synonymous_variant ORF1ab_pp1a L3879L 1.00e+0 B
V7397 11676C>T synonymous_variant ORF1ab_pp1a V3892V 8.16e-1 B
V7404 11709T>C synonymous_variant ORF1ab_pp1a D3903D 1.00e+0 B
V7411 11751T>C synonymous_variant ORF1ab_pp1a V3917V 1.00e+0 B
V742 2335G>A missense_variant ORF1ab_pp1a V779I 1.00e+0 B
V7421 11805G>T synonymous_variant ORF1ab_pp1a L3935L 1.00e+0 B
V7427 11850C>T synonymous_variant ORF1ab_pp1a S3950S 8.16e-1 B
V7439 11916T>C synonymous_variant ORF1ab_pp1a D3972D 1.00e+0 B
V7447 11988C>T synonymous_variant ORF1ab_pp1a A3996A 8.16e-1 B
V7453 12039T>C synonymous_variant ORF1ab_pp1a Y4013Y 1.00e+0 B
V7464 12135C>T synonymous_variant ORF1ab_pp1a L4045L 6.32e-1 B
V7496 12468C>T synonymous_variant ORF1ab_pp1a A4156A 1.00e+0 B
V7504 12516C>T synonymous_variant ORF1ab_pp1a Y4172Y 8.16e-1 B
V7517 12600T>C synonymous_variant ORF1ab_pp1a D4200D 1.00e+0 B
V7523 12627G>A synonymous_variant ORF1ab_pp1a L4209L 1.00e+0 B
V7552 12861G>T synonymous_variant ORF1ab_pp1a G4287G 8.16e-1 B
V7553 12873C>T synonymous_variant ORF1ab_pp1a I4291I 1.00e+0 B
V7572 12990C>T synonymous_variant ORF1ab_pp1a C4330C 6.32e-1 B
V7621 13353G>A synonymous_variant ORF1ab_pp1ab K4451K 1.00e+0 B
V7631 13449G>A synonymous_variant ORF1ab_pp1ab K4483K 8.16e-1 B
V7638 13530T>C synonymous_variant ORF1ab_pp1ab R4510R 1.00e+0 B
V7661 13770T>C synonymous_variant ORF1ab_pp1ab N4590N 7.07e-1 B
V7674 13839T>C synonymous_variant ORF1ab_pp1ab D4613D 1.00e+0 B
V7682 13914C>T synonymous_variant ORF1ab_pp1ab T4638T 7.07e-1 B
V7683 13917G>A synonymous_variant ORF1ab_pp1ab L4639L 8.16e-1 B
V7693 13971C>T synonymous_variant ORF1ab_pp1ab Y4657Y 8.16e-1 B
V7712 14118T>C synonymous_variant ORF1ab_pp1ab N4706N 8.16e-1 B
V7744 14335C>T synonymous_variant ORF1ab_pp1ab L4779L 6.32e-1 B
V7754 14379T>C synonymous_variant ORF1ab_pp1ab L4793L 1.00e+0 B
V7829 14973C>T synonymous_variant ORF1ab_pp1ab H4991H 6.32e-1 B
V7834 15009C>T synonymous_variant ORF1ab_pp1ab N5003N 8.16e-1 B
V7837 15033T>C synonymous_variant ORF1ab_pp1ab Y5011Y 8.16e-1 B
V7894 15499C>T synonymous_variant ORF1ab_pp1ab L5167L 8.16e-1 B
V7902 15570A>G synonymous_variant ORF1ab_pp1ab K5190K 1.00e+0 B
V7921 15688C>T synonymous_variant ORF1ab_pp1ab L5230L 1.00e+0 B
V7934 15753C>T synonymous_variant ORF1ab_pp1ab F5251F 1.00e+0 B
V7944 15870C>T synonymous_variant ORF1ab_pp1ab H5290H 1.00e+0 B
V7959 15996C>T synonymous_variant ORF1ab_pp1ab C5332C 1.00e+0 B
V7973 16113G>A synonymous_variant ORF1ab_pp1ab P5371P 1.00e+0 B
V7984 16164C>T synonymous_variant ORF1ab_pp1ab Y5388Y 8.16e-1 B
V7990 16215T>C synonymous_variant ORF1ab_pp1ab F5405F 8.16e-1 B
V7993 16257T>C synonymous_variant ORF1ab_pp1ab N5419N 8.16e-1 B
V8013 16392T>C synonymous_variant ORF1ab_pp1ab A5464A 1.00e+0 B
V8021 16464T>C synonymous_variant ORF1ab_pp1ab H5488H 1.00e+0 B
V8047 16690C>T synonymous_variant ORF1ab_pp1ab L5564L 6.32e-1 B
V8049 16704G>A synonymous_variant ORF1ab_pp1ab E5568E 1.00e+0 B
V8063 16803T>C synonymous_variant ORF1ab_pp1ab Y5601Y 1.00e+0 B
V8064 16815G>A synonymous_variant ORF1ab_pp1ab Q5605Q 1.00e+0 B
V8067 16855C>T synonymous_variant ORF1ab_pp1ab L5619L 1.00e+0 B
V8100 17070G>A synonymous_variant ORF1ab_pp1ab T5690T 1.00e+0 B
V8107 17139C>T synonymous_variant ORF1ab_pp1ab A5713A 7.07e-1 B
V8157 17478T>C synonymous_variant ORF1ab_pp1ab R5826R 1.00e+0 B
V8172 17586C>T synonymous_variant ORF1ab_pp1ab G5862G 7.07e-1 B
V8203 17853C>T synonymous_variant ORF1ab_pp1ab H5951H 1.00e+0 B
V8225 18039C>T synonymous_variant ORF1ab_pp1ab G6013G 1.00e+0 B
V8231 18063T>C synonymous_variant ORF1ab_pp1ab A6021A 1.00e+0 B
V8232 18084C>T synonymous_variant ORF1ab_pp1ab T6028T 7.07e-1 B
V8296 18492G>T synonymous_variant ORF1ab_pp1ab P6164P 1.00e+0 B
V8302 18549T>C synonymous_variant ORF1ab_pp1ab D6183D 1.00e+0 B
V8307 18564C>T synonymous_variant ORF1ab_pp1ab V6188V 6.32e-1 B
V8330 18717C>T synonymous_variant ORF1ab_pp1ab H6239H 1.00e+0 B
V8335 18765C>T synonymous_variant ORF1ab_pp1ab H6255H 6.32e-1 B
V8354 18900C>T synonymous_variant ORF1ab_pp1ab D6300D 1.00e+0 B
V8358 18921C>T synonymous_variant ORF1ab_pp1ab C6307C 1.00e+0 B
V8367 18991C>T synonymous_variant ORF1ab_pp1ab L6331L 1.00e+0 B
V8369 18999C>T synonymous_variant ORF1ab_pp1ab N6333N 1.00e+0 B
V8373 19047T>C synonymous_variant ORF1ab_pp1ab H6349H 1.00e+0 B
V8378 19116C>T synonymous_variant ORF1ab_pp1ab Y6372Y 1.00e+0 B
V8379 19119T>C synonymous_variant ORF1ab_pp1ab S6373S 1.00e+0 B
V8404 19326T>C synonymous_variant ORF1ab_pp1ab Y6442Y 1.00e+0 B
V8407 19338C>T synonymous_variant ORF1ab_pp1ab N6446N 8.16e-1 B
V8411 19392G>A synonymous_variant ORF1ab_pp1ab K6464K 1.00e+0 B
V8412 19398C>T synonymous_variant ORF1ab_pp1ab H6466H 1.00e+0 B
V8420 19536G>A synonymous_variant ORF1ab_pp1ab K6512K 1.00e+0 B
V8434 19611C>T synonymous_variant ORF1ab_pp1ab I6537I 1.00e+0 B
V8460 19827C>T synonymous_variant ORF1ab_pp1ab P6609P 1.00e+0 B
V8476 20019C>T synonymous_variant ORF1ab_pp1ab F6673F 1.00e+0 B
V8478 20043C>T synonymous_variant ORF1ab_pp1ab G6681G 1.00e+0 B
V8479 20046T>C synonymous_variant ORF1ab_pp1ab Y6682Y 1.00e+0 B
V852 2875C>T missense_variant ORF1ab_pp1a P959S 8.16e-1 B
V8530 20526C>T synonymous_variant ORF1ab_pp1ab V6842V 1.00e+0 B
V8535 20559C>T synonymous_variant ORF1ab_pp1ab N6853N 1.00e+0 B
V8539 20613T>C synonymous_variant ORF1ab_pp1ab G6871G 1.00e+0 B
V8541 20634A>T synonymous_variant ORF1ab_pp1ab P6878P 1.00e+0 B
V8553 20688A>T synonymous_variant ORF1ab_pp1ab S6896S 1.00e+0 B
V8554 20700C>T synonymous_variant ORF1ab_pp1ab D6900D 8.16e-1 B
V8556 20709T>C synonymous_variant ORF1ab_pp1ab S6903S 8.16e-1 B
V8563 20790C>T synonymous_variant ORF1ab_pp1ab Y6930Y 1.00e+0 B
V8564 20793C>T synonymous_variant ORF1ab_pp1ab D6931D 6.32e-1 B
V8573 20892C>T synonymous_variant ORF1ab_pp1ab S6964S 1.00e+0 B
V8588 20970C>T synonymous_variant ORF1ab_pp1ab A6990A 1.00e+0 B
V8590 20991G>A synonymous_variant ORF1ab_pp1ab A6997A 1.00e+0 B
V8601 21042C>T synonymous_variant ORF1ab_pp1ab R7014R 6.32e-1 B
V8604 21093T>C synonymous_variant ORF1ab_pp1ab N7031N 8.16e-1 B
V8608 21141A>G synonymous_variant ORF1ab_pp1ab K7047K 1.00e+0 B
V8610 21147C>T synonymous_variant ORF1ab_pp1ab P7049P 1.00e+0 B
V8616 21249C>T synonymous_variant ORF1ab_pp1ab N7083N 1.00e+0 B
V8617 21252C>T synonymous_variant ORF1ab_pp1ab N7084N 8.16e-1 B
V878 2966G>T missense_variant ORF1ab_pp1a G989V 1.00e+0 B
V8796 1284T>C synonymous_variant S D428D 7.07e-1 B
V8798 1293C>T synonymous_variant S G431G 7.07e-1 B
V883 2978G>A missense_variant ORF1ab_pp1a G993D 1.00e+0 B
V8858 1809T>C synonymous_variant S N603N 8.16e-1 B
V8861 1839G>A synonymous_variant S Q613Q 1.00e+0 B
V8921 2287T>C synonymous_variant S L763L 1.00e+0 B
V8923 2292C>T synonymous_variant S N764N 7.07e-1 B
V8927 2334C>T synonymous_variant S T778T 1.00e+0 B
V8929 2367C>T synonymous_variant S Y789Y 1.00e+0 B
V8931 2379A>T synonymous_variant S P793P 1.00e+0 B
V8932 2385A>G synonymous_variant S K795K 1.00e+0 B
V8937 2424T>C synonymous_variant S D808D 1.00e+0 B
V8941 2448A>G synonymous_variant S S816S 1.00e+0 B
V8944 2461C>T synonymous_variant S L821L 6.32e-1 B
V8949 2499C>T synonymous_variant S F833F 1.00e+0 B
V8952 2508A>G synonymous_variant S Q836Q 1.00e+0 B
V8956 2520C>T synonymous_variant S C840C 1.00e+0 B
V8963 2565T>C synonymous_variant S F855F 1.00e+0 B
V8966 2574T>C synonymous_variant S L858L 8.16e-1 B
V8976 2661C>T synonymous_variant S T887T 1.00e+0 B
V8982 2757C>T synonymous_variant S N919N 7.07e-1 B
V8985 2775C>T synonymous_variant S N925N 8.16e-1 B
V8997 2853G>T synonymous_variant S V951V 1.00e+0 B
V8998 2856C>T synonymous_variant S V952V 8.16e-1 B
V8999 2859C>T synonymous_variant S N953N 1.00e+0 B
V9000 2871A>G synonymous_variant S Q957Q 1.00e+0 B
V9005 2901C>T synonymous_variant S S967S 8.16e-1 B
V9017 3012G>A synonymous_variant S L1004L 1.00e+0 B
V9026 3135G>A synonymous_variant S K1045K 1.00e+0 B
V9030 3153C>T synonymous_variant S S1051S 1.00e+0 B
V9042 3219G>A synonymous_variant S K1073K 1.00e+0 B
V9048 3240C>T synonymous_variant S A1080A 1.00e+0 B
V905 3050C>T missense_variant ORF1ab_pp1a T1017I 8.16e-1 B
V9060 3342C>T synonymous_variant S I1114I 8.16e-1 B
V9074 3429T>A synonymous_variant S P1143P 1.00e+0 B
V9075 3433T>C synonymous_variant S L1145L 1.00e+0 B
V9082 3456A>G synonymous_variant S L1152L 1.00e+0 B
V9095 3534C>T synonymous_variant S N1178N 8.16e-1 B
V9099 3577T>C synonymous_variant S L1193L 1.00e+0 B
V9105 3594C>T synonymous_variant S I1198I 8.16e-1 B
V9118 3705C>T synonymous_variant S C1235C 7.07e-1 B
V9122 3735G>A synonymous_variant S K1245K 6.32e-1 B
V9123 3753A>G synonymous_variant S G1251G 1.00e+0 B
V9141 60C>T synonymous_variant ORF3a I20I 7.07e-1 B
V9170 186C>T synonymous_variant ORF3a I62I 7.07e-1 B
V9184 273C>T synonymous_variant ORF3a Y91Y 8.16e-1 B
V9197 327T>C synonymous_variant ORF3a Y109Y 1.00e+0 B
V9207 435T>C synonymous_variant ORF3a Y145Y 1.00e+0 B
V9208 444C>T synonymous_variant ORF3a C148C 1.00e+0 B
V9209 462C>T synonymous_variant ORF3a Y154Y 7.07e-1 B
V9271 87T>C synonymous_variant E V29V 1.00e+0 B
V9277 180T>C synonymous_variant E S60S 1.00e+0 B
V9296 84C>T synonymous_variant M F28F 6.32e-1 B
V9303 123C>T synonymous_variant M N41N 1.00e+0 B
V9316 231C>T synonymous_variant M T77T 8.16e-1 B
V9331 318G>A synonymous_variant M T106T 1.00e+0 B
V9335 339T>C synonymous_variant M N113N 7.07e-1 B
V9340 360C>T synonymous_variant M L120L 7.07e-1 B
V9345 372C>T synonymous_variant M L124L 7.07e-1 B
V9351 396G>T synonymous_variant M P132P 1.00e+0 B
V9353 405A>G synonymous_variant M E135E 6.32e-1 B
V9368 480C>T synonymous_variant M D160D 8.16e-1 B
V9381 552G>T synonymous_variant M S184S 1.00e+0 B
V9384 570C>T synonymous_variant M D190D 6.32e-1 B
V9387 606C>A synonymous_variant M G202G 1.00e+0 B
V9389 609C>T synonymous_variant M N203N 6.32e-1 B
V9390 612T>C synonymous_variant M Y204Y 1.00e+0 B
V9391 621C>T synonymous_variant M N207N 1.00e+0 B
V9403 75C>T synonymous_variant ORF6 S25S 1.00e+0 B
V9404 84T>C synonymous_variant ORF6 N28N 8.16e-1 B
V9407 96C>T synonymous_variant ORF6 I32I 7.07e-1 B
V9442 138T>C synonymous_variant ORF7a F46F 1.00e+0 B
V9446 156C>T synonymous_variant ORF7a N52N 1.00e+0 B
V9455 210C>T synonymous_variant ORF7a G70G 1.00e+0 B
V9477 297A>T synonymous_variant ORF7a P99P 8.16e-1 B
V9482 327T>C synonymous_variant ORF7a F109F 1.00e+0 B
V9483 339C>T synonymous_variant ORF7a C113C 1.00e+0 B
V9503 126C>T synonymous_variant ORF7b H42H 1.00e+0 B
V9509 30C>T synonymous_variant ORF8 I10I 8.16e-1 B
V9528 138T>C synonymous_variant ORF8 Y46Y 1.00e+0 B
V9563 27G>A synonymous_variant N Q9Q 1.00e+0 B
V9580 105G>A synonymous_variant N A35A 6.32e-1 B
V9589 123G>T synonymous_variant N R41R 1.00e+0 B
V9613 246C>T synonymous_variant N D82D 1.00e+0 B
V9623 330C>T synonymous_variant N F110F 8.16e-1 B
V9673 546C>T synonymous_variant N A182A 1.00e+0 B
V9712 771G>A synonymous_variant N K257K 1.00e+0 B
V9727 837A>T synonymous_variant N P279P 1.00e+0 B
V9747 924C>T synonymous_variant N A308A 8.16e-1 B
V9752 939G>A synonymous_variant N A313A 1.00e+0 B
V9791 1122G>A synonymous_variant N K374K 8.16e-1 B
V2078 10568C>T missense_variant ORF1ab_pp1a A3523V 9.04e-1 BN.1.2
V9191 300C>T synonymous_variant ORF3a G100G 7.50e-1 BN.1.2
V3402 20466G>T missense_variant ORF1ab_pp1ab K6822N 8.16e-1 BQ.1.1.11
V7984 16164C>T synonymous_variant ORF1ab_pp1ab Y5388Y 8.16e-1 BQ.1.1.11
V3805 857C>T missense_variant S T286I 7.07e-1 BQ.1.1.13
V291 544T>C missense_variant ORF1ab_pp1a Y182H 1.00e+0 BQ.1.1.22
V878 2966G>T missense_variant ORF1ab_pp1a G989V 7.07e-1 BQ.1.28
V232 346G>A missense_variant ORF1ab_pp1a V116M 7.07e-1 BQ.1
V2226 11324C>T missense_variant ORF1ab_pp1a T3775I 1.00e+0 CA.3
V9446 156C>T synonymous_variant ORF7a N52N 1.00e+0 CA.3
V9502 123T>C synonymous_variant ORF7b C41C 7.07e-1 CA.3
V43 -98T>C upstream_gene_variant ORF1ab_pp1a None 8.57e-1 Q.4
V8449 19719C>T synonymous_variant ORF1ab_pp1ab V6573V 8.57e-1 Q.4
V2755 15812A>G missense_variant ORF1ab_pp1ab D5271G 1.00e+0 R.1
V4640 784C>T missense_variant ORF3a P262S 7.07e-1 R.1
V8546 20667G>A synonymous_variant ORF1ab_pp1ab T6889T 7.07e-1 R.1
V7018 8640C>T synonymous_variant ORF1ab_pp1a D2880D 7.07e-1 XBB.1.9
V8945 2469C>T synonymous_variant S F823F 6.32e-1 XB





Manual curation of mutation (20143T>C)-related literature from PubMed

The pubmed.mineR and pubmed-mapper were utilized for extracting literature from PubMed, followed by manual filtering.
Note: PubMed: (COVID-19 [Title/Abstract] OR SARS-COV-2 [Title/Abstract]) AND (DNA mutation [Title/Abstract] OR Protein mutation-1 letter [Title/Abstract] OR Protein mutation-3 letter [Title/Abstract]).

DNA level Protein level Paper title Journal name Publication year Pubmed ID