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The current mutation

ID: V9000
DNA: 2871A>G
Protein: Q957Q
Position: 24433








COV2Var annotation categories







Summary information of mutation (2871A>G)

Basic Information about Mutation.

  Gene Information   Gene ID   GU280_gp02
  Gene Name   S
  Gene Type   protein_coding
  Genome position   24433
  Reference genome   GenBank ID: NC_045512.2
  Mutation type   synonymous_variant
  DNA Level   DNA Mutation: 2871A>G
  Ref Seq: A
  Mut Seq: G
  Protein Level   Protein 1-letter Mutation: Q957Q
  Protein 3-letter Mutation: Gln957Gln

Overview of the genomic positions of Mutation.
Note: The annotated 12 genes were retrieved from GeneBank (Accession: NC_045512.2). "MP" represents genomic position of mutation.





Analyzing the distribution of mutation (2871A>G) across geographic regions, temporal trends, and lineages

The count of genome sequences harboring this mutation and its distribution across global regions offer insights into regional variations.
Note: The distribution of mutation across 218 geographical regions. Color representation of genome sequence counts. The data is obtained from GISAID's metadata, specifically capturing the regional distribution of genomic sequences.



The dynamic count of genome sequences containing this mutation over time.
Note: Clicking the "Count" or "Cumulative Count" button toggles the view. Count represents the number of genome sequences per month. Cumulative count represents the accumulated total count up to the respective month. The data is obtained from GISAID's metadata, specifically capturing the collection date of genomic sequences.



For every time point represented in the graph above, identifying the top 3 lineages with the highest count of genome sequences carrying this mutation aids in pinpointing noteworthy lineages for further analysis.
Note: Users can filter the lineages by entering a "Year-Month" term in the search box. For example, entering 2020-01 will display lineages that appeared in January 2020. The data is obtained from GISAID's metadata, specifically capturing the collection date of genomic sequences.

Collection date Lineage Total lineage monthly counts Lineage-specific monthly counts Lineage-specific monthly frequency
2020-11 B.1.177.21 13 13 1.00e+0
2020-12 B.1.177.21 12 12 1.00e+0
2020-05 B 2 2 1.00e+0
2020-06 B.1.1.25 1 1 1.00e+0
2021-01 B.1.258 4 2 5.00e-1
2021-01 B.1.177.81 4 1 2.50e-1
2021-01 B.1.221 4 1 2.50e-1
2021-11 AY.112 32 28 8.75e-1
2021-11 AY.103 32 1 3.12e-2
2021-11 AY.122 32 1 3.12e-2
2021-12 AY.112 29 20 6.90e-1
2021-12 AY.103 29 3 1.03e-1
2021-12 BA.2.9 29 3 1.03e-1
2021-02 B.1.2 6 2 3.33e-1
2021-02 B.1 6 1 1.67e-1
2021-02 B.1.1.519 6 1 1.67e-1
2021-03 B.1.1.7 36 29 8.06e-1
2021-03 B.1.526 36 4 1.11e-1
2021-03 B.1.177.81 36 3 8.33e-2
2021-04 B.1.1.7 8 5 6.25e-1
2021-04 B.1.526 8 2 2.50e-1
2021-04 AY.112 8 1 1.25e-1
2021-05 B.1.1.7 19 14 7.37e-1
2021-05 Q.1 19 3 1.58e-1
2021-05 B.1.617.2 19 1 5.26e-2
2021-06 P.1 9 5 5.56e-1
2021-06 B.1.1.7 9 3 3.33e-1
2021-06 Q.1 9 1 1.11e-1
2021-07 B.1.1.7 21 14 6.67e-1
2021-07 P.1 21 5 2.38e-1
2021-07 AY.122 21 1 4.76e-2
2021-08 B.1.1.7 16 6 3.75e-1
2021-08 AY.44 16 4 2.50e-1
2021-08 AY.122 16 2 1.25e-1
2021-09 AY.44 14 4 2.86e-1
2021-09 B.1.617.2 14 3 2.14e-1
2021-09 AY.4 14 2 1.43e-1
2022-01 BA.2.9 105 91 8.67e-1
2022-01 BA.1.1 105 4 3.81e-2
2022-01 BA.2 105 3 2.86e-2
2022-10 BA.2.9 4 3 7.50e-1
2022-10 BA.4.6 4 1 2.50e-1
2022-11 BA.2.9 4 4 1.00e+0
2022-02 BA.2.9 638 612 9.59e-1
2022-02 BA.2 638 15 2.35e-2
2022-02 BA.1 638 4 6.27e-3
2022-03 BA.2.9 2071 1894 9.15e-1
2022-03 BA.2.9.1 2071 149 7.19e-2
2022-03 BA.2 2071 15 7.24e-3
2022-04 BA.2.9 3094 2708 8.75e-1
2022-04 BA.2.9.1 3094 303 9.79e-2
2022-04 BA.2 3094 27 8.73e-3
2022-05 BA.2.9 3184 2602 8.17e-1
2022-05 BA.2.9.1 3184 232 7.29e-2
2022-05 XAM 3184 128 4.02e-2
2022-06 BA.2.9 1575 1088 6.91e-1
2022-06 XAM 1575 229 1.45e-1
2022-06 XAF 1575 115 7.30e-2
2022-07 BA.2.9 234 173 7.39e-1
2022-07 XAM 234 19 8.12e-2
2022-07 XAF 234 14 5.98e-2
2022-08 BA.2.9 38 25 6.58e-1
2022-08 XAM 38 8 2.11e-1
2022-08 XAF 38 3 7.89e-2
2022-09 BA.5.1.22 5 2 4.00e-1
2022-09 BA.2.9 5 1 2.00e-1
2022-09 BA.4.6 5 1 2.00e-1
2023-01 CH.1.1.3 7 5 7.14e-1
2023-01 BQ.1.12 7 1 1.43e-1
2023-01 XBB.1 7 1 1.43e-1
2023-02 CH.1.1.1 1 1 1.00e+0

The count of genome sequences and the frequency of this mutation in each lineage.
Note: Displaying mutation frequencies (>0.01) among 2,735 lineages. Mutation Count represents the count of sequences carrying this mutation. Users can filter the lineages by entering a search term in the search box. For example, entering "A.1" will display A.1 lineages. The data is obtained from GISAID's metadata, specifically capturing the lineage of genomic sequences. Mutation count: Count of sequences carrying this mutation.

Mutation ID Lineage Mutation frequency Mutation count Earliest lineage emergence Latest lineage emergence
V9000 BA.2.43 7.10e-2 37 2022-3-10 2022-7-21
V9000 BA.2.9.1 1.00e+0 733 2022-2-26 2022-7-13
V9000 XAF 1.00e+0 215 2022-2-22 2022-8-25
V9000 XAM 9.98e-1 400 2022-3-19 2022-8-8
V9000 XAU 9.91e-1 110 2022-3-14 2022-7-14
V9000 BA.2.9 4.58e-2 9204 2021-6-30 2023-2-22






Examining mutation (2871A>G) found in abundant sequences of non-human animal hosts

Exploring mutation presence across 35 non-human animal hosts for cross-species transmission.
Note: We retained the mutation that appear in at least three non-human animal hosts' sequences. The data is obtained from GISAID's metadata, specifically capturing the host of genomic sequences.

Animal host Lineage Source region Collection date Accession ID




Association between mutation (2871A>G) and patients of different ages, genders, and statuses

Note: The logistic regression model was employed to examine changes in patient data before and after the mutation. The logistic regression model was conducted using the glm function in R. The data is obtained from GISAID's metadata, specifically capturing the patient status, gender, and age of genomic sequences.

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient statuses (ambulatory, deceased, homebound, hospitalized, mild, and recovered) based on GISAID classifications. In the analysis exploring the association between mutation and patient status, the model included mutation, patient status, patient age, gender, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient status Ambulatory 6.54e-1 2.17e-1 3.01e+0 2.58e-3 Increase
Deceased -1.96e+0 7.30e-1 -2.69e+0 7.24e-3 Decrease
Homebound 2.07e+1 2.52e+3 8.20e-3 9.93e-1 Increase
Hospitalized -1.18e+0 2.22e-1 -5.34e+0 9.35e-8 Decrease
Mild -1.77e+1 1.04e+3 -1.70e-2 9.86e-1 Decrease
Recovered 6.14e-1 2.91e-1 2.11e+0 3.47e-2 Increase

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient age (0-17, 18-39, 40-64, 65-84, and 85+). In the analysis exploring the association between mutation and patient age, the model included mutation, patient age, gender, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient age, years 0-17 6.54e-2 6.04e-2 1.08e+0 2.79e-1 Increase
18-39 1.17e-1 3.12e-2 3.75e+0 1.74e-4 Increase
40-64 -3.30e-2 3.13e-2 -1.05e+0 2.92e-1 Decrease
65-84 -2.17e-1 4.48e-2 -4.84e+0 1.32e-6 Decrease
>=85 3.95e-2 8.46e-2 4.66e-1 6.41e-1 Increase

Analyzing the association between mutation and patient status.
Note: we categorized the data into different patient gender (male and female). In the analysis exploring the association between mutation and patient gender, the model included mutation, patient gender, patient age, sequence region of origin, and sequence collection time point. In the 'increase' direction of the mutation, it means that when this mutation occurs, it increases the corresponding effect proportion. In the 'decrease' direction of the mutation, it means that when this mutation occurs, it decreases the corresponding effect proportion. A p-value lower than 0.001 signifies a notable differentiation between the population with and without the mutation.

Attribute Effect Estimate SE Z-value P-value Direction
Patient gender Male -6.47e-2 3.06e-2 -2.12e+0 3.43e-2 Decrease





Investigating natural selection at mutation (2871A>G) site for genetic adaptation and diversity

Note: Investigating the occurrence of positive selection or negative selection at this mutation site reveals implications for genetic adaptation and diversity.

The MEME method within the HyPhy software was employed to analyze positive selection. MEME: episodic selection.
Note: List of sites found to be under episodic selection by MEME (p < 0.05). "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site P-value Lineage Method

The FEL method within the HyPhy software was employed to analyze both positive and negative selection. FEL: pervasive selection on samll datasets.
Note: List of sites found to be under pervasive selection by FEL (p < 0.05). A beta value greater than alpha signifies positive selection, while a beta value smaller than alpha signifies negative selection. "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site Alpha Beta P-value Lineage Method

The FUBAR method within the HyPhy software was employed to analyze both positive and negative selection. FUBAR: pervasive selection on large datasets.
Note: List of sites found to be under pervasive selection by FUBAR (prob > 0.95). A prob[alpha < beta] value exceeding 0.95 indicates positive selection, while a prob[alpha > beta] value exceeding 0.95 indicates negative selection. "Protein Start" corresponds to the protein's starting genomic position. "Protein End" corresponds to the protein's ending genomic position. The term 'site' represents a selection site within the protein.

Protein name Protein start Protein end Protein length Site Prob[alpha>beta] Prob[alpha<beta] Lineage Method




Alterations in protein physicochemical properties induced by mutation (2871A>G)

Understanding the alterations in protein physicochemical properties can reveal the evolutionary processes and adaptive changes of viruses
Note: ProtParam software was used for the analysis of physicochemical properties. Significant change threshold: A change exceeding 10% compared to the reference is considered a significant change. "GRAVY" is an abbreviation for "grand average of hydropathicity".

Group Protein name Molecular weight Theoretical PI Extinction coefficients Aliphatic index GRAVY




Alterations in protein stability induced by mutation (2871A>G)

The impact of mutations on protein stability directly or indirectly affects the biological characteristics, adaptability, and transmission capacity of the virus
Note: iMutant 2.0 was utilized to analyze the effects of mutations on protein stability. pH 7 and a temperature of 25°C are employed to replicate the in vitro environment. pH 7.4 and a temperature of 37°C are utilized to simulate the in vivo environment.

Mutation Protein name Mutation type Position ΔDDG Stability pH Temperature Condition




Impact on protein function induced by mutation (2871A>G)

The impact of mutations on protein function
Note: The MutPred2 software was used to predict the pathogenicity of a mutation and gives the molecular mechanism of pathogenicity. A score above 0.5 indicates an increased likelihood of pathogenicity. "Pr" is the abbreviation for "proportion. P" is the abbreviation for "p-value.

Mutation Protein name Mutation type Score Molecular mechanisms




Exploring mutation (2871A>G) distribution within intrinsically disordered protein regions

Intrinsically Disordered Proteins (IDPs) which refers to protein regions that have no unique 3D structure. In viral proteins, mutations in the disordered regions s are critical for immune evasion and antibody escape, suggesting potential additional implications for vaccines and monoclonal therapeutic strategies.
Note: The iupred3 software was utilized for analyzing IDPs. A score greater than 0.5 is considered indicative of an IDP. In the plot, "POS" represents the position of the mutation.





Alterations in enzyme cleavage sites induced by mutation (2871A>G)

Exploring the impact of mutations on the cleavage sites of 28 enzymes.
Note: The PeptideCutter software was used for detecting enzymes cleavage sites. The increased enzymes cleavage sites refer to the cleavage sites in the mutated protein that are added compared to the reference protein. Conversely, the decreased enzymes cleavage sites indicate the cleavage sites in the mutated protein that are reduced compared to the reference protein.

Mutation Protein name Genome position Enzyme name Increased cleavage sites Decreased cleavage sites




Impact of spike protein mutation (2871A>G) on antigenicity and immunogenicity

Investigating the impact of mutations on antigenicity and immunogenicity carries important implications for vaccine design and our understanding of immune responses.
Note: An absolute change greater than 0.0102 (three times the median across sites) in antigenicity score is considered significant. An absolute changegreater than 0.2754 (three times the median across sites) in immunogenicity score is considered significant. The VaxiJen tool was utilized for antigenicity analysis. The IEDB tool was used for immunogenicity analysis. Antigens with a prediction score of more than 0.4 for this tool are considered candidate antigens. MHC I immunogenicity score >0, indicating a higher probability to stimulate an immune response.

Group Protein name Protein region Antigenicity score Immunogenicity score




Impact of mutation (2871A>G) on viral transmissibility by the affinity between RBD and ACE2 receptor

Unraveling the impact of mutations on the interaction between the receptor binding domain (RBD) and ACE2 receptor using deep mutational scanning (DMS) experimental data to gain insights into their effects on viral transmissibility.
Note: The ΔBinding affinity represents the disparity between the binding affinity of a mutation and the reference binding affinity. A positive Δbinding affinity value (Δlog10(KD,app) > 0) signifies an increased affinity between RBD and ACE2 receptor due to the mutation. Conversely, a negative value (Δlog10(KD,app) < 0) indicates a reduced affinity between RBD and ACE2 receptor caused by the mutation. A p-value smaller than 0.05 indicates significance. "Ave mut bind" represents the average binding affinity of this mutation. "Ave ref bind" refers to the average binding affinity at a site without any mutation (reference binding affinity).

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Mutation Protein name Protein region Mutation Position Ave mut bind Ave ref bind ΔBinding affinity P-value Image


The interface between the receptor binding domain (RBD) and ACE2 receptor is depicted in the crystal structure 6JM0.
Note: The structure 6M0J encompasses the RBD range of 333 to 526. The binding sites (403-406, 408, 417, 439, 445-447, 449, 453, 455-456, 473-478, 484-498, and 500-506) on the RBD that interface with ACE2 are indicated in magenta. The binding sites on the RBD that have been identified through the interface footprints experiment. The ACE2 binding sites within the interface are shown in cyan, representing residues within 5Å proximity to the RBD binding sites. The mutation within the RBD range of 333 to 526 is depicted in red.

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        Show interface residues:





Impact of mutation (2871A>G) on immune escape by the affinity between RBD and antibody/serum

By utilizing experimental data from deep mutational scanning (DMS), we can uncover how mutations affect the interaction between the receptor binding domain (RBD) and antibodies/serum. This approach provides valuable insights into strategies for evading the host immune response.
Note: We considered a mutation to mediate strong escape if the escape score exceeded 0.1 (10% of the maximum score of 1). A total of 1,504 antibodies/serum data were collected for this analysis. "Condition name" refers to the name of the antibodies/serum. "Mut escape score" represents the escape score of the mutation in that specific condition. "Avg mut escape score" indicates the average escape score of the mutation site in that condition, considering the occurrence of this mutation and other mutations. Class 1 antibodies bind to an epitope only in the RBD “up” conformation, and are the most abundant. Class 2 antibodies bind to the RBD both in “up” and “down” conformations. Class 3 and class 4 antibodies both bind outside the ACE2 binding site. Class 3 antibodies bind the RBD in both the open and closed conformation, while class 4 antibodies bind only in the open conformation.

Mutation Condition name Condition type Condition subtype Condition year Mut escape score Avg mut escape score




Investigating the co-mutation patterns of mutation (2871A>G) across 2,735 viral lineages

Investigating the co-mutation patterns of SARS-CoV-2 across 2,735 viral lineages to unravel the cooperative effects of different mutations. In biological research, correlation analysis of mutation sites helps us understand whether there is a close relationship or interaction between certain mutations.
Note: The Spearman correlation coefficient is used to calculate the correlation between two mutations within each Pango lineage. Holm–Bonferroni method was used for multiple test adjustment. We retained mutation pairs with correlation values greater than 0.6 or less than -0.6 and Holm–Bonferroni corrected p-values less than 0.05.

Associated mutation ID DNA mutation Mutation type Protein name Protein mutation correlation coefficient Lineage
V7902 15570A>G synonymous_variant ORF1ab_pp1ab K5190K 7.07e-1 AY.3
V7372 11499T>C synonymous_variant ORF1ab_pp1a N3833N 1.00e+0 BA.1.1.2
V9269 78C>T synonymous_variant E F26F 7.50e-1 P.1
V717 2260G>A missense_variant ORF1ab_pp1a E754K 7.07e-1 B.1.2
V2252 11572G>T missense_variant ORF1ab_pp1a V3858L 9.53e-1 AY.112
V7001 8553C>T synonymous_variant ORF1ab_pp1a C2851C 7.07e-1 B.1.1.519
V2378 12529G>A missense_variant ORF1ab_pp1a G4177R 8.94e-1 B.1.177.81
V7087 9180T>C synonymous_variant ORF1ab_pp1a L3060L 7.74e-1 B.1.177.81
V4317 48G>T missense_variant ORF3a K16N 7.07e-1 B.1.221
V7653 13698A>G synonymous_variant ORF1ab_pp1ab V4566V 7.07e-1 B.1.221
V2464 13271A>G missense_variant ORF1ab_pp1ab Y4424C 8.33e-1 B.1.526
V8054 16743T>C synonymous_variant ORF1ab_pp1ab N5581N 8.94e-1 BA.2.10.1
V7842 15078C>T synonymous_variant ORF1ab_pp1ab A5026A 7.07e-1 BA.2.36
V5650 1235G>T missense_variant N S412I 1.00e+0 BA.2.56
V6344 3345T>C synonymous_variant ORF1ab_pp1a L1115L 1.00e+0 BA.2.56
V7842 15078C>T synonymous_variant ORF1ab_pp1ab A5026A 1.00e+0 BA.2.56
V2207 11249C>T missense_variant ORF1ab_pp1a T3750I 7.90e-1 BA.2.9.3
V8302 18549T>C synonymous_variant ORF1ab_pp1ab D6183D 7.90e-1 BA.2.9.3
V8399 19290C>T synonymous_variant ORF1ab_pp1ab G6430G 7.45e-1 BA.2.9.3
V859 2900C>T missense_variant ORF1ab_pp1a A967V 6.32e-1 BA.2.9.3
V9284 6A>T synonymous_variant M A2A 1.00e+0 BA.2.9.5
V9671 537C>T synonymous_variant N G179G 1.00e+0 BA.2.9.5
V1069 3674G>A missense_variant ORF1ab_pp1a R1225K 1.00e+0 B
V1217 4697G>A missense_variant ORF1ab_pp1a R1566K 8.16e-1 B
V1319 5383A>C missense_variant ORF1ab_pp1a K1795Q 8.16e-1 B
V142 113T>C missense_variant ORF1ab_pp1a V38A 1.00e+0 B
V1424 6077A>G missense_variant ORF1ab_pp1a D2026G 1.00e+0 B
V1431 6097G>A missense_variant ORF1ab_pp1a A2033T 1.00e+0 B
V1457 6181G>A missense_variant ORF1ab_pp1a V2061I 1.00e+0 B
V3275 19697C>T missense_variant ORF1ab_pp1ab T6566M 8.16e-1 B
V3294 19783A>G missense_variant ORF1ab_pp1ab I6595V 1.00e+0 B
V3352 20143T>C missense_variant ORF1ab_pp1ab F6715L 1.00e+0 B
V3512 21259G>A missense_variant ORF1ab_pp1ab V7087I 1.00e+0 B
V393 998C>T missense_variant ORF1ab_pp1a T333M 8.16e-1 B
V4069 2314G>A missense_variant S V772I 6.32e-1 B
V4097 2521C>T missense_variant S L841F 1.00e+0 B
V4099 2530A>G missense_variant S I844V 1.00e+0 B
V4100 2533G>T missense_variant S A845S 7.07e-1 B
V4454 280C>T missense_variant ORF3a L94F 1.00e+0 B
V4577 628G>T missense_variant ORF3a D210Y 8.16e-1 B
V4634 776T>C missense_variant ORF3a V259A 1.00e+0 B
V4994 346C>T missense_variant ORF7a L116F 8.16e-1 B
V5199 316G>C missense_variant ORF8 E106Q 6.32e-1 B
V521 1492G>A missense_variant ORF1ab_pp1a A498T 1.00e+0 B
V5260 23A>G missense_variant N N8S 1.00e+0 B
V5325 109T>C missense_variant N S37P 6.32e-1 B
V58 -76C>T upstream_gene_variant ORF1ab_pp1a None 1.00e+0 B
V5807 *4385C>T downstream_gene_variant S None 7.07e-1 B
V5829 *4453C>T downstream_gene_variant S None 1.00e+0 B
V5857 114C>T synonymous_variant ORF1ab_pp1a V38V 1.00e+0 B
V5880 246T>C synonymous_variant ORF1ab_pp1a G82G 1.00e+0 B
V5885 264G>A synonymous_variant ORF1ab_pp1a L88L 1.00e+0 B
V5920 441C>T synonymous_variant ORF1ab_pp1a D147D 8.16e-1 B
V5929 510C>T synonymous_variant ORF1ab_pp1a T170T 1.00e+0 B
V5932 534C>T synonymous_variant ORF1ab_pp1a N178N 8.16e-1 B
V5955 655C>T synonymous_variant ORF1ab_pp1a L219L 1.00e+0 B
V5980 822A>G synonymous_variant ORF1ab_pp1a V274V 1.00e+0 B
V5983 829T>C synonymous_variant ORF1ab_pp1a L277L 1.00e+0 B
V5988 861G>A synonymous_variant ORF1ab_pp1a R287R 1.00e+0 B
V5990 885C>T synonymous_variant ORF1ab_pp1a G295G 6.32e-1 B
V5998 921G>T synonymous_variant ORF1ab_pp1a A307A 1.00e+0 B
V6013 1017C>T synonymous_variant ORF1ab_pp1a A339A 1.00e+0 B
V6014 1023C>T synonymous_variant ORF1ab_pp1a C341C 7.07e-1 B
V6020 1078T>C synonymous_variant ORF1ab_pp1a L360L 1.00e+0 B
V6036 1215C>T synonymous_variant ORF1ab_pp1a A405A 1.00e+0 B
V6045 1284C>T synonymous_variant ORF1ab_pp1a S428S 8.16e-1 B
V6051 1323A>G synonymous_variant ORF1ab_pp1a E441E 8.16e-1 B
V6052 1329C>T synonymous_variant ORF1ab_pp1a S443S 6.32e-1 B
V6054 1344C>T synonymous_variant ORF1ab_pp1a D448D 1.00e+0 B
V6056 1350T>C synonymous_variant ORF1ab_pp1a L450L 1.00e+0 B
V6058 1374A>G synonymous_variant ORF1ab_pp1a K458K 1.00e+0 B
V6092 1635A>G synonymous_variant ORF1ab_pp1a R545R 8.16e-1 B
V6101 1695C>T synonymous_variant ORF1ab_pp1a A565A 6.32e-1 B
V6102 1708C>T synonymous_variant ORF1ab_pp1a L570L 8.16e-1 B
V6120 1830G>A synonymous_variant ORF1ab_pp1a S610S 1.00e+0 B
V6144 1962C>T synonymous_variant ORF1ab_pp1a T654T 1.00e+0 B
V6151 2016G>A synonymous_variant ORF1ab_pp1a K672K 1.00e+0 B
V6164 2133G>A synonymous_variant ORF1ab_pp1a T711T 1.00e+0 B
V6177 2185C>T synonymous_variant ORF1ab_pp1a L729L 8.16e-1 B
V6182 2220C>T synonymous_variant ORF1ab_pp1a I740I 1.00e+0 B
V6192 2268T>C synonymous_variant ORF1ab_pp1a V756V 1.00e+0 B
V6205 2379C>T synonymous_variant ORF1ab_pp1a I793I 1.00e+0 B
V6208 2388A>G synonymous_variant ORF1ab_pp1a T796T 1.00e+0 B
V6219 2445C>T synonymous_variant ORF1ab_pp1a L815L 8.16e-1 B
V6222 2466G>A synonymous_variant ORF1ab_pp1a K822K 1.00e+0 B
V6229 2523C>T synonymous_variant ORF1ab_pp1a I841I 1.00e+0 B
V6244 2613C>T synonymous_variant ORF1ab_pp1a F871F 8.16e-1 B
V6245 2616C>T synonymous_variant ORF1ab_pp1a A872A 1.00e+0 B
V6248 2649G>A synonymous_variant ORF1ab_pp1a L883L 1.00e+0 B
V6273 2826G>A synonymous_variant ORF1ab_pp1a E942E 1.00e+0 B
V6296 3024T>C synonymous_variant ORF1ab_pp1a V1008V 8.16e-1 B
V6316 3177T>C synonymous_variant ORF1ab_pp1a N1059N 1.00e+0 B
V6324 3222C>T synonymous_variant ORF1ab_pp1a A1074A 6.32e-1 B
V6369 3573G>A synonymous_variant ORF1ab_pp1a L1191L 1.00e+0 B
V6371 3609C>T synonymous_variant ORF1ab_pp1a I1203I 7.07e-1 B
V6384 3747C>T synonymous_variant ORF1ab_pp1a L1249L 1.00e+0 B
V6386 3756C>T synonymous_variant ORF1ab_pp1a N1252N 8.16e-1 B
V6391 3792T>C synonymous_variant ORF1ab_pp1a H1264H 7.07e-1 B
V6394 3804C>T synonymous_variant ORF1ab_pp1a A1268A 6.32e-1 B
V6410 3924C>T synonymous_variant ORF1ab_pp1a G1308G 1.00e+0 B
V6411 3927T>C synonymous_variant ORF1ab_pp1a T1309T 1.00e+0 B
V6415 3969C>T synonymous_variant ORF1ab_pp1a D1323D 8.16e-1 B
V6422 4011C>T synonymous_variant ORF1ab_pp1a Y1337Y 6.32e-1 B
V6423 4020G>A synonymous_variant ORF1ab_pp1a E1340E 1.00e+0 B
V6428 4066C>T synonymous_variant ORF1ab_pp1a L1356L 7.07e-1 B
V6440 4158C>T synonymous_variant ORF1ab_pp1a R1386R 8.16e-1 B
V6445 4179G>T synonymous_variant ORF1ab_pp1a V1393V 8.16e-1 B
V6446 4191C>T synonymous_variant ORF1ab_pp1a A1397A 8.16e-1 B
V6447 4218T>C synonymous_variant ORF1ab_pp1a Y1406Y 1.00e+0 B
V6452 4269C>T synonymous_variant ORF1ab_pp1a Y1423Y 8.16e-1 B
V6455 4296G>A synonymous_variant ORF1ab_pp1a A1432A 8.16e-1 B
V6463 4321C>T synonymous_variant ORF1ab_pp1a L1441L 7.07e-1 B
V6467 4368C>T synonymous_variant ORF1ab_pp1a G1456G 8.16e-1 B
V6475 4401A>G synonymous_variant ORF1ab_pp1a R1467R 7.07e-1 B
V6480 4455G>A synonymous_variant ORF1ab_pp1a A1485A 1.00e+0 B
V6491 4545C>T synonymous_variant ORF1ab_pp1a S1515S 1.00e+0 B
V6496 4611C>T synonymous_variant ORF1ab_pp1a Y1537Y 7.07e-1 B
V6497 4617T>C synonymous_variant ORF1ab_pp1a S1539S 1.00e+0 B
V6520 4743G>A synonymous_variant ORF1ab_pp1a T1581T 1.00e+0 B
V6536 4863A>G synonymous_variant ORF1ab_pp1a L1621L 1.00e+0 B
V6538 4879C>T synonymous_variant ORF1ab_pp1a L1627L 7.07e-1 B
V6552 4953T>C synonymous_variant ORF1ab_pp1a N1651N 8.16e-1 B
V6555 4974C>T synonymous_variant ORF1ab_pp1a Y1658Y 6.32e-1 B
V6565 5040G>A synonymous_variant ORF1ab_pp1a L1680L 8.16e-1 B
V6568 5067G>A synonymous_variant ORF1ab_pp1a K1689K 1.00e+0 B
V6569 5073T>C synonymous_variant ORF1ab_pp1a N1691N 8.16e-1 B
V6571 5083C>T synonymous_variant ORF1ab_pp1a L1695L 1.00e+0 B
V6575 5107A>C synonymous_variant ORF1ab_pp1a R1703R 1.00e+0 B
V6578 5142C>T synonymous_variant ORF1ab_pp1a I1714I 1.00e+0 B
V6580 5157T>C synonymous_variant ORF1ab_pp1a N1719N 1.00e+0 B
V6583 5202C>T synonymous_variant ORF1ab_pp1a Y1734Y 8.16e-1 B
V6591 5247C>T synonymous_variant ORF1ab_pp1a N1749N 6.32e-1 B
V6598 5283C>T synonymous_variant ORF1ab_pp1a T1761T 1.00e+0 B
V6616 5400G>A synonymous_variant ORF1ab_pp1a Q1800Q 8.16e-1 B
V6627 5508T>C synonymous_variant ORF1ab_pp1a Y1836Y 8.16e-1 B
V6632 5568C>T synonymous_variant ORF1ab_pp1a S1856S 7.07e-1 B
V6649 5709C>T synonymous_variant ORF1ab_pp1a D1903D 1.00e+0 B
V6652 5730A>G synonymous_variant ORF1ab_pp1a Q1910Q 1.00e+0 B
V6654 5760T>C synonymous_variant ORF1ab_pp1a Y1920Y 1.00e+0 B
V6662 5802T>C synonymous_variant ORF1ab_pp1a N1934N 1.00e+0 B
V6666 5880C>T synonymous_variant ORF1ab_pp1a F1960F 7.07e-1 B
V6676 5931C>T synonymous_variant ORF1ab_pp1a P1977P 1.00e+0 B
V6680 5961T>C synonymous_variant ORF1ab_pp1a H1987H 1.00e+0 B
V6683 5997T>C synonymous_variant ORF1ab_pp1a N1999N 1.00e+0 B
V6684 6003C>T synonymous_variant ORF1ab_pp1a A2001A 1.00e+0 B
V6688 6018T>C synonymous_variant ORF1ab_pp1a N2006N 1.00e+0 B
V6693 6069T>C synonymous_variant ORF1ab_pp1a N2023N 1.00e+0 B
V6701 6093G>A synonymous_variant ORF1ab_pp1a E2031E 8.16e-1 B
V6719 6168C>T synonymous_variant ORF1ab_pp1a T2056T 1.00e+0 B
V6728 6264A>G synonymous_variant ORF1ab_pp1a E2088E 1.00e+0 B
V6746 6399C>T synonymous_variant ORF1ab_pp1a V2133V 1.00e+0 B
V6753 6441C>T synonymous_variant ORF1ab_pp1a N2147N 6.32e-1 B
V6755 6471T>C synonymous_variant ORF1ab_pp1a V2157V 1.00e+0 B
V6770 6618C>T synonymous_variant ORF1ab_pp1a V2206V 1.00e+0 B
V6777 6703C>T synonymous_variant ORF1ab_pp1a L2235L 1.00e+0 B
V6817 7002C>T synonymous_variant ORF1ab_pp1a F2334F 8.16e-1 B
V6826 7092T>C synonymous_variant ORF1ab_pp1a L2364L 1.00e+0 B
V6829 7128G>A synonymous_variant ORF1ab_pp1a P2376P 1.00e+0 B
V6836 7170T>C synonymous_variant ORF1ab_pp1a F2390F 1.00e+0 B
V6842 7263C>T synonymous_variant ORF1ab_pp1a V2421V 7.07e-1 B
V6849 7329C>T synonymous_variant ORF1ab_pp1a G2443G 1.00e+0 B
V6852 7344C>T synonymous_variant ORF1ab_pp1a H2448H 7.07e-1 B
V6854 7368T>C synonymous_variant ORF1ab_pp1a D2456D 8.16e-1 B
V6878 7575C>T synonymous_variant ORF1ab_pp1a D2525D 8.16e-1 B
V6898 7746T>C synonymous_variant ORF1ab_pp1a D2582D 1.00e+0 B
V6913 7827C>T synonymous_variant ORF1ab_pp1a L2609L 6.32e-1 B
V6927 7911T>C synonymous_variant ORF1ab_pp1a A2637A 1.00e+0 B
V6928 7914G>A synonymous_variant ORF1ab_pp1a R2638R 1.00e+0 B
V693 2167T>C missense_variant ORF1ab_pp1a S723P 1.00e+0 B
V6962 8199T>C synonymous_variant ORF1ab_pp1a A2733A 1.00e+0 B
V7015 8613C>T synonymous_variant ORF1ab_pp1a G2871G 1.00e+0 B
V7017 8622A>G synonymous_variant ORF1ab_pp1a L2874L 7.07e-1 B
V7034 8805T>C synonymous_variant ORF1ab_pp1a D2935D 1.00e+0 B
V7109 9378T>C synonymous_variant ORF1ab_pp1a I3126I 1.00e+0 B
V7173 9783T>C synonymous_variant ORF1ab_pp1a V3261V 1.00e+0 B
V7185 9891C>T synonymous_variant ORF1ab_pp1a D3297D 8.16e-1 B
V721 2269G>A missense_variant ORF1ab_pp1a V757I 1.00e+0 B
V7220 10185C>T synonymous_variant ORF1ab_pp1a P3395P 6.32e-1 B
V7243 10359A>G synonymous_variant ORF1ab_pp1a T3453T 1.00e+0 B
V7286 10725A>G synonymous_variant ORF1ab_pp1a T3575T 1.00e+0 B
V7291 10755C>T synonymous_variant ORF1ab_pp1a L3585L 7.07e-1 B
V7293 10785C>T synonymous_variant ORF1ab_pp1a V3595V 7.07e-1 B
V7296 10812T>C synonymous_variant ORF1ab_pp1a F3604F 1.00e+0 B
V7306 10935C>T synonymous_variant ORF1ab_pp1a A3645A 1.00e+0 B
V7331 11190C>T synonymous_variant ORF1ab_pp1a A3730A 8.16e-1 B
V7360 11439C>T synonymous_variant ORF1ab_pp1a Y3813Y 6.32e-1 B
V7361 11454G>A synonymous_variant ORF1ab_pp1a Q3818Q 1.00e+0 B
V7362 11463A>G synonymous_variant ORF1ab_pp1a R3821R 1.00e+0 B
V7381 11547C>T synonymous_variant ORF1ab_pp1a G3849G 1.00e+0 B
V7382 11559C>T synonymous_variant ORF1ab_pp1a I3853I 6.32e-1 B
V739 2327C>T missense_variant ORF1ab_pp1a A776V 7.07e-1 B
V7391 11637C>T synonymous_variant ORF1ab_pp1a L3879L 1.00e+0 B
V7397 11676C>T synonymous_variant ORF1ab_pp1a V3892V 8.16e-1 B
V7404 11709T>C synonymous_variant ORF1ab_pp1a D3903D 1.00e+0 B
V7411 11751T>C synonymous_variant ORF1ab_pp1a V3917V 1.00e+0 B
V742 2335G>A missense_variant ORF1ab_pp1a V779I 1.00e+0 B
V7421 11805G>T synonymous_variant ORF1ab_pp1a L3935L 1.00e+0 B
V7427 11850C>T synonymous_variant ORF1ab_pp1a S3950S 8.16e-1 B
V7439 11916T>C synonymous_variant ORF1ab_pp1a D3972D 1.00e+0 B
V7447 11988C>T synonymous_variant ORF1ab_pp1a A3996A 8.16e-1 B
V7453 12039T>C synonymous_variant ORF1ab_pp1a Y4013Y 1.00e+0 B
V7464 12135C>T synonymous_variant ORF1ab_pp1a L4045L 6.32e-1 B
V7496 12468C>T synonymous_variant ORF1ab_pp1a A4156A 1.00e+0 B
V7504 12516C>T synonymous_variant ORF1ab_pp1a Y4172Y 8.16e-1 B
V7517 12600T>C synonymous_variant ORF1ab_pp1a D4200D 1.00e+0 B
V7523 12627G>A synonymous_variant ORF1ab_pp1a L4209L 1.00e+0 B
V7552 12861G>T synonymous_variant ORF1ab_pp1a G4287G 8.16e-1 B
V7553 12873C>T synonymous_variant ORF1ab_pp1a I4291I 1.00e+0 B
V7572 12990C>T synonymous_variant ORF1ab_pp1a C4330C 6.32e-1 B
V7621 13353G>A synonymous_variant ORF1ab_pp1ab K4451K 1.00e+0 B
V7631 13449G>A synonymous_variant ORF1ab_pp1ab K4483K 8.16e-1 B
V7638 13530T>C synonymous_variant ORF1ab_pp1ab R4510R 1.00e+0 B
V7661 13770T>C synonymous_variant ORF1ab_pp1ab N4590N 7.07e-1 B
V7674 13839T>C synonymous_variant ORF1ab_pp1ab D4613D 1.00e+0 B
V7682 13914C>T synonymous_variant ORF1ab_pp1ab T4638T 7.07e-1 B
V7683 13917G>A synonymous_variant ORF1ab_pp1ab L4639L 8.16e-1 B
V7693 13971C>T synonymous_variant ORF1ab_pp1ab Y4657Y 8.16e-1 B
V7712 14118T>C synonymous_variant ORF1ab_pp1ab N4706N 8.16e-1 B
V7744 14335C>T synonymous_variant ORF1ab_pp1ab L4779L 6.32e-1 B
V7754 14379T>C synonymous_variant ORF1ab_pp1ab L4793L 1.00e+0 B
V7829 14973C>T synonymous_variant ORF1ab_pp1ab H4991H 6.32e-1 B
V7834 15009C>T synonymous_variant ORF1ab_pp1ab N5003N 8.16e-1 B
V7837 15033T>C synonymous_variant ORF1ab_pp1ab Y5011Y 8.16e-1 B
V7894 15499C>T synonymous_variant ORF1ab_pp1ab L5167L 8.16e-1 B
V7902 15570A>G synonymous_variant ORF1ab_pp1ab K5190K 1.00e+0 B
V7921 15688C>T synonymous_variant ORF1ab_pp1ab L5230L 1.00e+0 B
V7934 15753C>T synonymous_variant ORF1ab_pp1ab F5251F 1.00e+0 B
V7944 15870C>T synonymous_variant ORF1ab_pp1ab H5290H 1.00e+0 B
V7959 15996C>T synonymous_variant ORF1ab_pp1ab C5332C 1.00e+0 B
V7973 16113G>A synonymous_variant ORF1ab_pp1ab P5371P 1.00e+0 B
V7984 16164C>T synonymous_variant ORF1ab_pp1ab Y5388Y 8.16e-1 B
V7990 16215T>C synonymous_variant ORF1ab_pp1ab F5405F 8.16e-1 B
V7993 16257T>C synonymous_variant ORF1ab_pp1ab N5419N 8.16e-1 B
V8013 16392T>C synonymous_variant ORF1ab_pp1ab A5464A 1.00e+0 B
V8021 16464T>C synonymous_variant ORF1ab_pp1ab H5488H 1.00e+0 B
V8047 16690C>T synonymous_variant ORF1ab_pp1ab L5564L 6.32e-1 B
V8049 16704G>A synonymous_variant ORF1ab_pp1ab E5568E 1.00e+0 B
V8063 16803T>C synonymous_variant ORF1ab_pp1ab Y5601Y 1.00e+0 B
V8064 16815G>A synonymous_variant ORF1ab_pp1ab Q5605Q 1.00e+0 B
V8067 16855C>T synonymous_variant ORF1ab_pp1ab L5619L 1.00e+0 B
V8100 17070G>A synonymous_variant ORF1ab_pp1ab T5690T 1.00e+0 B
V8107 17139C>T synonymous_variant ORF1ab_pp1ab A5713A 7.07e-1 B
V8157 17478T>C synonymous_variant ORF1ab_pp1ab R5826R 1.00e+0 B
V8172 17586C>T synonymous_variant ORF1ab_pp1ab G5862G 7.07e-1 B
V8203 17853C>T synonymous_variant ORF1ab_pp1ab H5951H 1.00e+0 B
V8225 18039C>T synonymous_variant ORF1ab_pp1ab G6013G 1.00e+0 B
V8231 18063T>C synonymous_variant ORF1ab_pp1ab A6021A 1.00e+0 B
V8232 18084C>T synonymous_variant ORF1ab_pp1ab T6028T 7.07e-1 B
V8296 18492G>T synonymous_variant ORF1ab_pp1ab P6164P 1.00e+0 B
V8302 18549T>C synonymous_variant ORF1ab_pp1ab D6183D 1.00e+0 B
V8307 18564C>T synonymous_variant ORF1ab_pp1ab V6188V 6.32e-1 B
V8330 18717C>T synonymous_variant ORF1ab_pp1ab H6239H 1.00e+0 B
V8335 18765C>T synonymous_variant ORF1ab_pp1ab H6255H 6.32e-1 B
V8354 18900C>T synonymous_variant ORF1ab_pp1ab D6300D 1.00e+0 B
V8358 18921C>T synonymous_variant ORF1ab_pp1ab C6307C 1.00e+0 B
V8367 18991C>T synonymous_variant ORF1ab_pp1ab L6331L 1.00e+0 B
V8369 18999C>T synonymous_variant ORF1ab_pp1ab N6333N 1.00e+0 B
V8373 19047T>C synonymous_variant ORF1ab_pp1ab H6349H 1.00e+0 B
V8378 19116C>T synonymous_variant ORF1ab_pp1ab Y6372Y 1.00e+0 B
V8379 19119T>C synonymous_variant ORF1ab_pp1ab S6373S 1.00e+0 B
V8404 19326T>C synonymous_variant ORF1ab_pp1ab Y6442Y 1.00e+0 B
V8407 19338C>T synonymous_variant ORF1ab_pp1ab N6446N 8.16e-1 B
V8411 19392G>A synonymous_variant ORF1ab_pp1ab K6464K 1.00e+0 B
V8412 19398C>T synonymous_variant ORF1ab_pp1ab H6466H 1.00e+0 B
V8420 19536G>A synonymous_variant ORF1ab_pp1ab K6512K 1.00e+0 B
V8434 19611C>T synonymous_variant ORF1ab_pp1ab I6537I 1.00e+0 B
V8460 19827C>T synonymous_variant ORF1ab_pp1ab P6609P 1.00e+0 B
V8476 20019C>T synonymous_variant ORF1ab_pp1ab F6673F 1.00e+0 B
V8478 20043C>T synonymous_variant ORF1ab_pp1ab G6681G 1.00e+0 B
V8479 20046T>C synonymous_variant ORF1ab_pp1ab Y6682Y 1.00e+0 B
V852 2875C>T missense_variant ORF1ab_pp1a P959S 8.16e-1 B
V8530 20526C>T synonymous_variant ORF1ab_pp1ab V6842V 1.00e+0 B
V8535 20559C>T synonymous_variant ORF1ab_pp1ab N6853N 1.00e+0 B
V8539 20613T>C synonymous_variant ORF1ab_pp1ab G6871G 1.00e+0 B
V8541 20634A>T synonymous_variant ORF1ab_pp1ab P6878P 1.00e+0 B
V8553 20688A>T synonymous_variant ORF1ab_pp1ab S6896S 1.00e+0 B
V8554 20700C>T synonymous_variant ORF1ab_pp1ab D6900D 8.16e-1 B
V8556 20709T>C synonymous_variant ORF1ab_pp1ab S6903S 8.16e-1 B
V8563 20790C>T synonymous_variant ORF1ab_pp1ab Y6930Y 1.00e+0 B
V8564 20793C>T synonymous_variant ORF1ab_pp1ab D6931D 6.32e-1 B
V8573 20892C>T synonymous_variant ORF1ab_pp1ab S6964S 1.00e+0 B
V8588 20970C>T synonymous_variant ORF1ab_pp1ab A6990A 1.00e+0 B
V8590 20991G>A synonymous_variant ORF1ab_pp1ab A6997A 1.00e+0 B
V8601 21042C>T synonymous_variant ORF1ab_pp1ab R7014R 6.32e-1 B
V8604 21093T>C synonymous_variant ORF1ab_pp1ab N7031N 8.16e-1 B
V8608 21141A>G synonymous_variant ORF1ab_pp1ab K7047K 1.00e+0 B
V8610 21147C>T synonymous_variant ORF1ab_pp1ab P7049P 1.00e+0 B
V8616 21249C>T synonymous_variant ORF1ab_pp1ab N7083N 1.00e+0 B
V8617 21252C>T synonymous_variant ORF1ab_pp1ab N7084N 8.16e-1 B
V878 2966G>T missense_variant ORF1ab_pp1a G989V 1.00e+0 B
V8796 1284T>C synonymous_variant S D428D 7.07e-1 B
V8798 1293C>T synonymous_variant S G431G 7.07e-1 B
V883 2978G>A missense_variant ORF1ab_pp1a G993D 1.00e+0 B
V8858 1809T>C synonymous_variant S N603N 8.16e-1 B
V8861 1839G>A synonymous_variant S Q613Q 1.00e+0 B
V8921 2287T>C synonymous_variant S L763L 1.00e+0 B
V8923 2292C>T synonymous_variant S N764N 7.07e-1 B
V8927 2334C>T synonymous_variant S T778T 1.00e+0 B
V8929 2367C>T synonymous_variant S Y789Y 1.00e+0 B
V8931 2379A>T synonymous_variant S P793P 1.00e+0 B
V8932 2385A>G synonymous_variant S K795K 1.00e+0 B
V8937 2424T>C synonymous_variant S D808D 1.00e+0 B
V8941 2448A>G synonymous_variant S S816S 1.00e+0 B
V8944 2461C>T synonymous_variant S L821L 6.32e-1 B
V8949 2499C>T synonymous_variant S F833F 1.00e+0 B
V8952 2508A>G synonymous_variant S Q836Q 1.00e+0 B
V8956 2520C>T synonymous_variant S C840C 1.00e+0 B
V8963 2565T>C synonymous_variant S F855F 1.00e+0 B
V8966 2574T>C synonymous_variant S L858L 8.16e-1 B
V8976 2661C>T synonymous_variant S T887T 1.00e+0 B
V8982 2757C>T synonymous_variant S N919N 7.07e-1 B
V8985 2775C>T synonymous_variant S N925N 8.16e-1 B
V8997 2853G>T synonymous_variant S V951V 1.00e+0 B
V8998 2856C>T synonymous_variant S V952V 8.16e-1 B
V8999 2859C>T synonymous_variant S N953N 1.00e+0 B
V9005 2901C>T synonymous_variant S S967S 8.16e-1 B
V9017 3012G>A synonymous_variant S L1004L 1.00e+0 B
V9026 3135G>A synonymous_variant S K1045K 1.00e+0 B
V9030 3153C>T synonymous_variant S S1051S 1.00e+0 B
V9042 3219G>A synonymous_variant S K1073K 1.00e+0 B
V9048 3240C>T synonymous_variant S A1080A 1.00e+0 B
V905 3050C>T missense_variant ORF1ab_pp1a T1017I 8.16e-1 B
V9060 3342C>T synonymous_variant S I1114I 8.16e-1 B
V9074 3429T>A synonymous_variant S P1143P 1.00e+0 B
V9075 3433T>C synonymous_variant S L1145L 1.00e+0 B
V9082 3456A>G synonymous_variant S L1152L 1.00e+0 B
V9095 3534C>T synonymous_variant S N1178N 8.16e-1 B
V9099 3577T>C synonymous_variant S L1193L 1.00e+0 B
V9105 3594C>T synonymous_variant S I1198I 8.16e-1 B
V9118 3705C>T synonymous_variant S C1235C 7.07e-1 B
V9122 3735G>A synonymous_variant S K1245K 6.32e-1 B
V9123 3753A>G synonymous_variant S G1251G 1.00e+0 B
V9141 60C>T synonymous_variant ORF3a I20I 7.07e-1 B
V9170 186C>T synonymous_variant ORF3a I62I 7.07e-1 B
V9184 273C>T synonymous_variant ORF3a Y91Y 8.16e-1 B
V9197 327T>C synonymous_variant ORF3a Y109Y 1.00e+0 B
V9207 435T>C synonymous_variant ORF3a Y145Y 1.00e+0 B
V9208 444C>T synonymous_variant ORF3a C148C 1.00e+0 B
V9209 462C>T synonymous_variant ORF3a Y154Y 7.07e-1 B
V9271 87T>C synonymous_variant E V29V 1.00e+0 B
V9277 180T>C synonymous_variant E S60S 1.00e+0 B
V9296 84C>T synonymous_variant M F28F 6.32e-1 B
V9303 123C>T synonymous_variant M N41N 1.00e+0 B
V9316 231C>T synonymous_variant M T77T 8.16e-1 B
V9331 318G>A synonymous_variant M T106T 1.00e+0 B
V9335 339T>C synonymous_variant M N113N 7.07e-1 B
V9340 360C>T synonymous_variant M L120L 7.07e-1 B
V9345 372C>T synonymous_variant M L124L 7.07e-1 B
V9351 396G>T synonymous_variant M P132P 1.00e+0 B
V9353 405A>G synonymous_variant M E135E 6.32e-1 B
V9368 480C>T synonymous_variant M D160D 8.16e-1 B
V9381 552G>T synonymous_variant M S184S 1.00e+0 B
V9384 570C>T synonymous_variant M D190D 6.32e-1 B
V9387 606C>A synonymous_variant M G202G 1.00e+0 B
V9389 609C>T synonymous_variant M N203N 6.32e-1 B
V9390 612T>C synonymous_variant M Y204Y 1.00e+0 B
V9391 621C>T synonymous_variant M N207N 1.00e+0 B
V9403 75C>T synonymous_variant ORF6 S25S 1.00e+0 B
V9404 84T>C synonymous_variant ORF6 N28N 8.16e-1 B
V9407 96C>T synonymous_variant ORF6 I32I 7.07e-1 B
V9442 138T>C synonymous_variant ORF7a F46F 1.00e+0 B
V9446 156C>T synonymous_variant ORF7a N52N 1.00e+0 B
V9455 210C>T synonymous_variant ORF7a G70G 1.00e+0 B
V9477 297A>T synonymous_variant ORF7a P99P 8.16e-1 B
V9482 327T>C synonymous_variant ORF7a F109F 1.00e+0 B
V9483 339C>T synonymous_variant ORF7a C113C 1.00e+0 B
V9503 126C>T synonymous_variant ORF7b H42H 1.00e+0 B
V9509 30C>T synonymous_variant ORF8 I10I 8.16e-1 B
V9528 138T>C synonymous_variant ORF8 Y46Y 1.00e+0 B
V9563 27G>A synonymous_variant N Q9Q 1.00e+0 B
V9580 105G>A synonymous_variant N A35A 6.32e-1 B
V9589 123G>T synonymous_variant N R41R 1.00e+0 B
V9613 246C>T synonymous_variant N D82D 1.00e+0 B
V9623 330C>T synonymous_variant N F110F 8.16e-1 B
V9673 546C>T synonymous_variant N A182A 1.00e+0 B
V9712 771G>A synonymous_variant N K257K 1.00e+0 B
V9727 837A>T synonymous_variant N P279P 1.00e+0 B
V9747 924C>T synonymous_variant N A308A 8.16e-1 B
V9752 939G>A synonymous_variant N A313A 1.00e+0 B
V9791 1122G>A synonymous_variant N K374K 8.16e-1 B
V5554 867G>C missense_variant N Q289H 1.00e+0 BQ.1.12
V3481 21037C>A missense_variant ORF1ab_pp1ab P7013T 8.45e-1 CH.1.1.3
V5401 464C>T missense_variant N A155V 7.07e-1 CH.1.1.3
V7796 14664C>T synonymous_variant ORF1ab_pp1ab N4888N 6.45e-1 CH.1.1.3
V386 958C>T missense_variant ORF1ab_pp1a L320F 1.00e+0 Q.1
V4178 3235C>T missense_variant S P1079S 6.71e-1 Q.1
V7964 16044C>T synonymous_variant ORF1ab_pp1ab F5348F 7.07e-1 Q.1
V4438 232C>T missense_variant ORF3a H78Y 1.00e+0 BA.2.58
V6116 1797C>T synonymous_variant ORF1ab_pp1a A599A 1.00e+0 BA.2.58
V7331 11190C>T synonymous_variant ORF1ab_pp1a A3730A 1.00e+0 BA.2.58
V8400 19296C>T synonymous_variant ORF1ab_pp1ab S6432S 1.00e+0 BA.2.58
V8434 19611C>T synonymous_variant ORF1ab_pp1ab I6537I 1.00e+0 BA.2.58
V8653 213T>C synonymous_variant S S71S 1.00e+0 BA.2.58
V9603 180C>T synonymous_variant N G60G 1.00e+0 BA.2.58
V4144 2862A>T missense_variant S Q954H 1.00e+0 XAM
V6576 5121T>G synonymous_variant ORF1ab_pp1a A1707A 7.06e-1 XAM





Manual curation of mutation (2871A>G)-related literature from PubMed

The pubmed.mineR and pubmed-mapper were utilized for extracting literature from PubMed, followed by manual filtering.
Note: PubMed: (COVID-19 [Title/Abstract] OR SARS-COV-2 [Title/Abstract]) AND (DNA mutation [Title/Abstract] OR Protein mutation-1 letter [Title/Abstract] OR Protein mutation-3 letter [Title/Abstract]).

DNA level Protein level Paper title Journal name Publication year Pubmed ID